Protein Alignment CG8051 and slc16a4

DIOPT Version :10

• Sequence 1: NP_573377.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_001074068.2
• Gene: slc16a4 / 567144
• ZFINID: ZDB-GENE-070112-602
• Length: 558
• Species: Danio rerio
• Alignment Length: 624
• Identity: 149/624 - (23%)
• Similarity: 252/624 - (40%)
• Gaps: 118/624 - (18%)

  Fly    24 LPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWLV 88
            ||:||        .|.|:|...|        .:.:..|| .||::.|....|   .|||||||:|
Zfish     2 LPKEQ--------HSDGKTAKTP--------CSELKAKV-MKKEKKKVVYRE---PPDGGWGWMV 46

  Fly    89 SV-ASGVNILVTFALAQQFGILF---RDRMAGLGISSSELTTIINTQIAVSAFTGLLNGPL---- 145
            .: ...||:||...| :.|||.|   :|...|...|.|.:.:|:::       ..|..|||
Zfish    47 VLHCFLVNVLVMGTL-KTFGIFFVALQDEFGGSSESISWIGSIMSS-------LRLSGGPLASVA 103

  Fly   146 FRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVKRR 210
            ..:...||.::||::....|..:.:||.:.....:|..::.|.|..|...|:|:.:.|||  ::|
Zfish   104 CAKLGNRVTSIVGALFVSAGFLFSIFATSVTYLYISMGLVVGLGFALLYQATSVVIVTYF--RKR 166

  Fly   211 TATAFQFGVAGLG-PIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVKRDRD 274
            .|||:..|.:|:| ......|...:|.::..||..|:..|..|:.:|..::.:|:
Zfish   167 LATAYSIGRSGMGLTFALAPFTQLLLDQYAWQGALLILGGLMLNLVASGMLLRPI---------- 221

  Fly   275 AEALQQVQPLAER--EDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEKSDS 337
             .......|::..  ...::|.:||.:...|||   ||             ||       .||||
Zfish   222 -NIRHPASPISNSTIHKTEKDPLKNNMNGNTPV---AN-------------GT-------SKSDS 262

  Fly   338 NGHVELKRLSSKDSNPGRQLRSISVSH-SIKEEEATGYN-SDHEVQHTELTEKEKQELEDEKERQ 400
            :..:....|..|  ||..:..|:  .| .:|:....|.| :|.....|.........::...|..
Zfish   263 SPPIHKDTLIIK--NPVHEQNSL--PHLDLKKPTQNGVNGTDSSQTKTSPEMNGVSPVDSLLENG 323

  Fly   401 RRKKLPFYMKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTP-FILS----DLGFNKDQI 460
            |.:.:|.....|:  |..||::..:.     |...:.|....|...| |.||    :||.:....
Zfish   324 RTENVPENSPKVL--DFSLLKNPFFC-----IYTWSLVFSQLAYFIPYFHLSARARNLGIDPMDA 381

  Fly   461 ALAMSTLGFFDLVVRFLIPLITAKINLSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAIFLWLGL 525
            :..:|..|..:.|.:.....:|.: ||.::..:....|.:|.....||..:..|:::.::
Zfish   382 SFIISVAGITETVAQLASGWVTDR-NLVHKYHYHKAYLILCGVVNLLSPLATSYILLMVY----- 440

  Fly   526 NKAFRTVFWSLIIPSYVPLKRLPAAAGL----QLLMSGTFSMIF--------GPLIGLIRDHT-S 577
                 .||:::....|:.| .||....|    :|..|..|||.|        .||.|.:.|:| :
Zfish   441 -----AVFFAIFCGGYMAL-LLPVLVDLVGADKLNNSMGFSMFFVGLGCLTGPPLAGFLYDYTQT 499

  Fly   578 YAVTLNLLNALCVMAFAGWYLEDFIRARSRKSPPVKSIN 616
            |..:..|.....:::....:||...|....:...::::|
Zfish   500 YDCSFYLAGVCYLLSSISLFLEPLARRWQARKERLETLN 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_573377.1	MFS_MCT_SLC16	85..599	CDD:340910	126/544 (23%)
slc16a4	NP_001074068.2	MFS_MCT5	43..526	CDD:340979	128/549 (23%)