DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8051 and CG14196

DIOPT Version :9

Sequence 1:	NP_001285434.1	Gene:	CG8051 / 32925	FlyBaseID:	FBgn0031012	Length:	616	Species:	Drosophila melanogaster
Sequence 2:	NP_573367.1	Gene:	CG14196 / 32915	FlyBaseID:	FBgn0031002	Length:	600	Species:	Drosophila melanogaster

Alignment Length:	596	Identity:	274/596 - (45%)
Similarity:	371/596 - (62%)	Gaps:	67/596 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 KRDKSDLGEDFVAPDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSSELTTIINTQ 131
            |.||||||:||||||.||.|:|.||:||:.|..:...||||.|||:|::.||:|||::|.|||..
  Fly    24 KHDKSDLGDDFVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINAN 88

  Fly   132 IAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSA 196
            .||||.|||||||:|||:|:|.||:.||:|....|....|.:||..|::::::|:|||.|::|||
  Fly    89 PAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSA 153

  Fly   197 SSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIY 261
            ||||:||||:.|||.|..|.:.:.|||||..|:..|::|..:||||||||||..|||:..|:|||
  Fly   154 SSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIY 218

  Fly   262 QPVKWHV-------VKRDRDAEAL------QQVQPLAERED----------QDEDIIK---NVVE 300
            |||::||       ..:::.||||      ||     :||.          ||:|..:   .:.|
  Fly   219 QPVRYHVKPPVEQLADQEQQAEALCAHCSWQQ-----KREPGGIFSSQYLCQDDDAQRPGYEICE 278

  Fly   301 PETPVLPRANDGWFGSRASLNSVGTRNRLNTWEKSDSNGHVELKRLS---SKDSN--------PG 354
            |.||:|.||||||:|||.||    |..||.....|.|....:.:||.   |::.|        |.
  Fly   279 PGTPMLSRANDGWYGSRLSL----TSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPN 339

  Fly   355 RQLRSISVSH---------SIKEEEATGYNSDHEVQHTELTE--KEKQELEDEKERQRRKKLPFY 408
            ...|....|:         |.|.||   :|::.:.:..|..|  .|...|.|       .::.|.
  Fly   340 NFRRERVESNLEAKLCCQCSAKREE---HNNNRKEKEAEAEEAGMESAPLHD-------PQMSFL 394

  Fly   409 MKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTPFILSDLGFNKDQIALAMSTLGFFDLV 473
            .|||.|||:|||||.|:|||..|:|:|||.|:||:|||||||.|.||:..||.||||.|...|:.
  Fly   395 AKVVTFFDLDLLRDFTFVNLVAGLTIINFGELNFSILTPFILVDFGFDTPQITLAMSLLAGLDIT 459

  Fly   474 VRFLIPLITAKINLSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAIFLWLGLNKAFRTVFWSLII 538
            :||::|.:|.||...||.||::|::|:.:||..::.|.::.:::..|:|:||.|..||:||.|||
  Fly   460 MRFMVPFLTEKIPWDNRVFFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTIFWPLII 524

  Fly   539 PSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHTSYAVTLNLLNALCVMAFAGWYLEDFIR 603
            |.||||.|||.|:|||||:||.|::|.||.:||:||...|:|||:.||.:..:|...|.||..||
  Fly   525 PGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRYDYSVTLHCLNMMSFVAATSWSLEALIR 589

  Fly   604 ARSRKSPPVKS 614
            ...||...|.|
  Fly   590 RHRRKQRLVNS 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	99/179 (55%)
		MFS	<428..598	CDD:119392	86/169 (51%)
		MFS_1	440..>572	CDD:284993	68/131 (52%)
CG14196	NP_573367.1	MFS	71..>221	CDD:119392	82/149 (55%)
CG14196	NP_573367.1	MFS	<410..579	CDD:119392	87/168 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444761
Domainoid	1	1.000	56	1.000	Domainoid score	I2686
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	1	1.000	-	-		H64368
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28161
OrthoDB	1	1.010	-	-		D215513at33208
OrthoFinder	1	1.000	-	-		FOG0010010
OrthoInspector	1	1.000	-	-		otm50074
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
	11	10.860