Protein Alignment CG8051 and SLC16A8

DIOPT Version :9

• Sequence 1: NP_001285434.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_037488.2
• Gene: SLC16A8 / 23539
• HGNCID: 16270
• Length: 504
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 113/539 - (20%)
• Similarity: 182/539 - (33%)
• Gaps: 144/539 - (26%)

  Fly    80 PDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSSELTTIINTQIAVSAFTGLLNGP 144
            |||||||:|..|..|.....:...:...:.||..|.......|:...:.:..:|:...||.::..
Human    13 PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTGPVSSI 77

  Fly   145 LFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVKR 209
            |..|:..|.|.|.|.:|...|:....||.......::..:|.|.|..|....|.:.:..||:.:|
Human    78 LVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRR 142

  Fly   210 RTATAFQFGVAGLGPIVCPYFAT-------YMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWH 267
            ..|.    |:|..|   .|.|.:       .:|..||.:|..||..|..||..||..:.:|
Human   143 PLAN----GLAAAG---SPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRP---- 196

  Fly   268 VVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTW 332
                                             |..|          |.|...:|.|.|
Human   197 ---------------------------------PPGP----------GPRPRRDSAGDR------ 212

  Fly   333 EKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELEDEK 397
             ..|:.|..|.       ...|.|||..|                                  .:
Human   213 -AGDAPGEAEA-------DGAGLQLREAS----------------------------------PR 235

  Fly   398 ERQRRKKLPFYMKVVIFFDMDLLRD-------ITYVNLAVGITLINFVEINFAILTPFILSDLGF 455
            .|.||:.|          |:.:..|       :|...:|:|:.:...:.:|:|       .|.|.
Human   236 VRPRRRLL----------DLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYA-------KDAGV 283

  Fly   456 NKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRT-----FFVVGILGMCIGRMFLSMTSNFYV 515
            .....|..:|.:||.|:|.|   |...|...|:...     .|.:.:|...:..:..:...::..
Human   284 PDTDAAFLLSIVGFVDIVAR---PACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGA 345

  Fly   516 MMAIFLWLGLNKAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRD-HTSYA 579
            ::|..:..||:..........::.:.|...|.|:|.||.||:.....:|..|..|.:.| ..:|.
Human   346 LVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYE 410

  Fly   580 VTLNLLNALCVMAFAGWYL 598
            :...|..:  .:|.||.::
Human   411 IIFYLAGS--EVALAGVFM 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_001285434.1	MFS	86..>266	CDD:119392	47/186 (25%)
		MFS	<428..598	CDD:119392	38/175 (22%)
		MFS_1	440..>572	CDD:284993	30/136 (22%)
SLC16A8	NP_037488.2	2A0113	1..460	CDD:273325	113/539 (21%)
		MFS	19..429	CDD:119392	107/533 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..224		11/88 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	441..504

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145517
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850