Protein Alignment CG8051 and gem-1

DIOPT Version :10

• Sequence 1: NP_573377.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Sequence 2: NP_001379120.1
• Gene: gem-1 / 181458
• WormBaseID: WBGene00008214
• Length: 771
• Species: Caenorhabditis elegans
• Alignment Length: 736
• Identity: 134/736 - (18%)
• Similarity: 252/736 - (34%)
• Gaps: 258/736 - (35%)

  Fly    63 PAKKKRDKSD------LGEDFVAPDGGWGWLVSVASGVNILVTFALAQQFGILF----RDRMAGL 117
            |...:.|.||      |.|..|..|||:||||.:||.:...|....:..|||:|    .....|.
 Worm    44 PVSARSDDSDAESVESLTERPVYKDGGYGWLVVLASFLMHAVCDGASFCFGIVFVKIQEHFQCGR 108

  Fly   118 GISSSELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSF 182
            .:|....:..::..:.:|...|:::..|..|.:..:.|.:.:|...:.:        |..:|..|
 Worm   109 FVSMITASMFLSLPLIMSPVAGIVSDILGCRMSIIIGASICTVSCIIAM--------FCSHIFFF 165

  Fly   183 SILYGFGRGLTVS----ASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCP--------YFATYML 235
            .|.:|.|.|:.:|    |:.:.|..||:.:|..||:|.....|:|.::.|        |.|:::
 Worm   166 MISFGLGCGVGMSFIYNAAIVIVTYYFEKRRGLATSFAVSGTGVGTVIYPILLNLSMIYLASFV- 229

  Fly   236 YEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVKRDRDAEALQQVQPLAEREDQDED------- 293
              ..::...:.||.............:.|:|...|.|......|:.  :|:.:|:.|:
 Worm   230 --SDIRIILIFFAVMYFVIAVIGFFIKDVEWESDKTDFKLRKFQKY--IAKMDDEKENNTNPTDA 290

  Fly   294 IIKNVVE-PETPVL----------------PRAND--------GWFGSRASLNSVGTRNRLNTWE 333
            .:::.:. |...:|                .|.:|        ..|.::..::|:...:.|||
 Worm   291 FMRHAISLPNLNILNNHSGSIQSICDAAKAERKSDKPTRSKSVALFDNKHQMSSIPEYSMLNT-- 353

  Fly   334 KSDSNGHVELKRLSSKDSNPGRQLRSI--SVSHSIK-----EEEATGYN---------------- 375
            ...:..|::|:..:|..:....|.|.:  .||.|:.     |:||...|
 Worm   354 NLANLEHLDLELANSPCTTVRAQRRRVISKVSMSVDQINELEDEAFHINLFQSSTESESDDESSS 418

  Fly   376 ------SDHEVQHTELTEKEKQE---------LEDEK---------------------------- 397
                  :|.:...:||:||...|         ||:..
 Worm   419 DDSEMSNDGDSSSSELSEKNLDEPTTKLINKNLENVAFRATSSVPNSARMNRNSVAAGTSNMFGG 483

  Fly   398 -----------------------------ERQRRKKL-----------------PFYMKVV---- 412
                                         .|:.||.:                 |.|.:|:
 Worm   484 RVIASNAIQSRHATNLIAMGKIPSAPMLVARKNRKSMIGKPIQGFYKKWLETEKPIYQEVIHCRA 548

  Fly   413 ----------IFF------------DMDLLR----DITYVNLAVGITLINFVEINFAILTPFILS 451
                      ::|            .:|.|:    :..|:..::||:  ||:    ::|....|:
 Worm   549 YIYLALSVLCLYFILDVPYVCFYEYSIDTLKMEESEANYIYYSIGIS--NFI----SVLLFGTLA 607

  Fly   452 DLGFNKDQIALAMSTLG-----FFDLVVRFLIPLITAKINLSNRTFFVVGILGMCIGRMFLSMTS 511
            |..........|.|.:|     .|...:..|:.|:               |:|:|.|   :::||
 Worm   608 DWTRKHITTIYASSMVGVGITIMFSTRINSLVELV---------------IVGVCFG---VTITS 654

  Fly   512 NFYVMMAIFLWLGLNKAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHT 576
            | ||:.:|                |:...:..:.....|..|..::.|..|:|..|:..|:|:.|
 Worm   655 N-YVLQSI----------------LVTICFEDVNLFQVAYSLIAMIEGVASLIGPPIFALVREAT 702

  Fly   577 SYAVTLNLLNALCVMAFAGWY 597
            .....:..::.:..:| :|::
 Worm   703 GGYTVVFFISGIFALA-SGFF 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8051	NP_573377.1	MFS_MCT_SLC16	85..599	CDD:340910	124/708 (18%)
gem-1	NP_001379120.1	MFS	72..>254	CDD:475125	42/192 (22%)
		MFS	<543..727	CDD:475125	40/222 (18%)