Protein Alignment CG8034 and SLC16A7

DIOPT Version :10

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: XP_011537291.1
• Gene: SLC16A7 / 9194
• HGNCID: 10928
• Length: 504
• Species: Homo sapiens
• Alignment Length: 697
• Identity: 135/697 - (19%)
• Similarity: 217/697 - (31%)
• Gaps: 260/697 - (37%)

  Fly     1 MASKQPRKVAPDGGWGWVACFGVSLVNLATRSIEPSFGL-------------LFGDTLKE----- 47
            |.|..|....|||||||:      :|..|..||..|:..             :|..|..|
Human     4 MPSAPPVHPPPDGGWGWI------VVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWIS 62

  Fly    48 ---LNVGTTGAAV-----IISALDVCMNF--SGLFVGP----LLKEFSYRKVAIAGSLLCGLGLA 98
               |.|...|..:     |.::|.:..:|  ||..:||    |:.::..|.|.|||.|||.||:.
Human    63 SIMLAVMYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGLLCCLGMV 127

  Fly    99 LTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVR 163
            |.|.::|:..:..|...|.|:|:..:...|...:..||..||..|.||:|||:.:.:..:....:
Human   128 LASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQ 192

  Fly   164 ILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDDEELMCISALPTPQPQLTVGGAGG 228
            .|...:.::|:.|:|..:.|||.|...|::|:.
Human   193 YLFNTFGWKGSFLILGSLLLNACVAGSLMRPLG-------------------------------- 225

  Fly   229 AASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTF 293
                                  |...|           |..||
Human   226 ----------------------PNQTT-----------SKSKN---------------------- 235

  Fly   294 PRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVTSNLSYMDFTGSILQVHLNTGDDE 358
                                                                       .||..|
Human   236 -----------------------------------------------------------KTGKTE 241

  Fly   359 FEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAAAALDEEAKKKAK-KPGFWRRFAD 422
                                                         |:.:.||.| |...|.:...
Human   242 ---------------------------------------------DDSSPKKIKTKKSTWEKVNK 261

  Fly   423 LLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTPFFFANL----------GYQKTDVAFCLSITA 477
            .||..:.|.:.||..|.|..|.::.          |||.:          |..:...||.||:.|
Human   262 YLDFSLFKHRGFLIYLSGNVIMFLG----------FFAPIIFLAPYAKDQGIDEYSAAFLLSVMA 316

  Fly   478 ITDIAARIVLPPIFDRTTIKKRT--IFLVSIIFVALTRSIMAEQTEWTQLMIWLSICGFFRGSAL 540
            ..|:.||..:..|.:...|:.|.  .|..:|:|..:...:.....::|.|:::....|...||..
Human   317 FVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVS 381

  Fly   541 SNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDSYPICIHTQSVCIMICATA 605
            |....|:.:.....:..||.|...:.:...|:...||.|.:.|:|..|.. ::.....|::.|:.
Human   382 SVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKY-MYMSCGAIVVAASV 445

  Fly   606 W-----GIEYLVEYIQSRRRTADAAQLPTQDVGATTTATSDQNDVKL 647
            |     .|.|  ..:...|:..:|.|...:....:.:..|:..:||:
Human   446 WLLIGNAINY--RLLAKERKEENARQKTRESEPLSKSKHSEDVNVKV 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	16..>193	CDD:475125	58/208 (28%)
		MFS	<428..609	CDD:475125	44/197 (22%)
SLC16A7	XP_011537291.1	2A0113	15..484	CDD:273325	128/678 (19%)