Protein Alignment CG8034 and SLC16A4

DIOPT Version :9

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_004687.1
• Gene: SLC16A4 / 9122
• HGNCID: 10925
• Length: 487
• Species: Homo sapiens
• Alignment Length: 627
• Identity: 122/627 - (19%)
• Similarity: 223/627 - (35%)
• Gaps: 166/627 - (26%)

  Fly     4 KQPRKVAP-----DGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKEL-----NVGTTGAAVI 58
            |:..||.|     ||||||:......|||:....:..:|.:.|....:|.     .:|..|:  |
Human     3 KREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGS--I 65

  Fly    59 ISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGL 123
            :|:|..|   :|..|..:......:..:|.|:.:...|..::|.|||:..:..|..::.|:|...
Human    66 MSSLRFC---AGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAF 127

  Fly   124 STSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVG 188
            ....|.|....|||.:...:..::.:|..:..|:.| ..:.|::.||:.||::|...:|||....
Human   128 LYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAP-FTKFLIDLYDWTGALILFGAIALNLVPS 191

  Fly   189 SVLLQPVKWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEM 253
            |:||:|:  |:|.|                     ..:|            ||:.|:...|
Human   192 SMLLRPI--HIKSE---------------------NNSG------------IKDKGSSLSA---- 217

  Fly   254 NTLLFHKPH-PHQHSMRKNYSEMAMNTMNGS---RLGIPKRPTFPRIMSLAGVQSAAHGAGGDSG 314
                    | |..|:...:..|...:|:..|   :.|:|.:
Human   218 --------HGPEAHATETHCHETEESTIKDSTTQKAGLPSK------------------------ 250

  Fly   315 GYTSQAEVNATQLRCRKASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLG 379
                    |.|        |:.|.|                 :||..                 |
Human   251 --------NLT--------VSQNQS-----------------EEFYN-----------------G 265

  Fly   380 GHRDSFIKMKPTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIF 444
            .:|:..:.....|.||      .:....|:             |.||.:.::..|  .:|..| |
Human   266 PNRNRLLLKSDEESDK------VISWSCKQ-------------LFDISLFRNPFF--YIFTWS-F 308

  Fly   445 YVAEMNFKMVTPFFFA---NLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSI 506
            .::::.:.:.|....|   .||....|.::.:|:..|.:..::|:...:.|:..|||.......:
Human   309 LLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSYL 373

  Fly   507 IFVALTRSIMAEQTEWTQLMIWLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFV 571
            |...:|..:....|.:..||.:......|.|..|:.....:.:.|....:....|.......:.|
Human   374 ILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAV 438

  Fly   572 ITFGPLIGLIRDVTDSYPICIHTQSVCIMICATAWGIEYLVE 613
            ::..|:.|.:.|.|.:|....:...:|.::.:.::....|.|
Human   439 LSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAE 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	45/181 (25%)
		MFS	<437..583	CDD:119392	28/148 (19%)
		MFS_1	437..>581	CDD:284993	28/146 (19%)
SLC16A4	NP_004687.1	MFS	24..477	CDD:119392	110/601 (18%)
		MFS_1	27..442	CDD:284993	104/563 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..250		13/67 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820