Protein Alignment CG8034 and SLC16A6

DIOPT Version :9

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: XP_005257846.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 527
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 120/615 - (19%)
• Similarity: 204/615 - (33%)
• Gaps: 187/615 - (30%)

  Fly    11 PDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGP 75
            |||||||........|.:.|..|..:||:.|.|.:...|...:..:.|||.....:.||......
Human    23 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATV 87

  Fly    76 LLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYFKHKR 140
            |...|.:|.|.:.|.||...|:...|.:..::|:.....:|:|:|...|.......|:.||..:|
Human    88 LSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRR 152

  Fly   141 GQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDD 205
            .....::..|....:......:..|.|...:|.::|.:..:.||..:...||:|:
Human   153 SIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPI---------- 207

  Fly   206 EELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRK 270
                               ...|.||.     |::.::..:|                .|:.:..
Human   208 -------------------FIRGPASP-----KIVIQENRKE----------------AQYMLEN 232

  Fly   271 NYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVT 335
            ..:..:::::                               |||
Human   233 EKTRTSIDSI-------------------------------DSG--------------------- 245

  Fly   336 SNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAA 400
                          |.|.|..                              |..||..:.:.|..
Human   246 --------------VELTTSP------------------------------KNVPTHTNLELEPK 266

  Fly   401 AALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFL-NLLFGLSIFYVAEMNFKMVTPFFFA---- 460
            |.:.:...|.:.:|.  .:.|.|||..:||:|.|: ..||||           ..|..|||
Human   267 ADMQQVLVKTSPRPS--EKKAPLLDFSILKEKSFICYALFGL-----------FATLGFFAPSLY 318

  Fly   461 ------NLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSIIFVALTRSIMAEQ 519
                  :||..:...||.||..||.::..||....:.:|..|:|..|.|:.:|.:.::.......
Human   319 IIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFA 383

  Fly   520 TEWTQLMIWLSICGFFRGSALSNF------TLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLI 578
            ||:..||    .|..|.|..:...      .|...:...:||:.||.|.::..:::..:...||.
Human   384 TEFWGLM----SCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLA 444

  Fly   579 GLIRDVTDSYPICIHT-------QSVCIMI 601
            ||:.|.:..|....::       .:||:.:
Human   445 GLLVDQSKIYSRAFYSCAAGMALAAVCLAL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	41/176 (23%)
		MFS	<437..583	CDD:119392	41/161 (25%)
		MFS_1	437..>581	CDD:284993	40/159 (25%)
SLC16A6	XP_005257846.2	2A0113	23..512	CDD:273325	120/615 (20%)
		MFS	33..476	CDD:119392	113/605 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3970
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810