Protein Alignment CG8034 and SLC16A6

DIOPT Version :10

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: XP_024306789.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 542
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 120/615 - (19%)
• Similarity: 204/615 - (33%)
• Gaps: 187/615 - (30%)

  Fly    11 PDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGP 75
            |||||||........|.:.|..|..:||:.|.|.:...|...:..:.|||.....:.||......
Human    38 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATV 102

  Fly    76 LLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYFKHKR 140
            |...|.:|.|.:.|.||...|:...|.:..::|:.....:|:|:|...|.......|:.||..:|
Human   103 LSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRR 167

  Fly   141 GQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDD 205
            .....::..|....:......:..|.|...:|.::|.:..:.||..:...||:|:
Human   168 SIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPI---------- 222

  Fly   206 EELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRK 270
                               ...|.||.     |::.::..:|                .|:.:..
Human   223 -------------------FIRGPASP-----KIVIQENRKE----------------AQYMLEN 247

  Fly   271 NYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVT 335
            ..:..:::::                               |||
Human   248 EKTRTSIDSI-------------------------------DSG--------------------- 260

  Fly   336 SNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAA 400
                          |.|.|..                              |..||..:.:.|..
Human   261 --------------VELTTSP------------------------------KNVPTHTNLELEPK 281

  Fly   401 AALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFL-NLLFGLSIFYVAEMNFKMVTPFFFA---- 460
            |.:.:...|.:.:|.  .:.|.|||..:||:|.|: ..||||           ..|..|||
Human   282 ADMQQVLVKTSPRPS--EKKAPLLDFSILKEKSFICYALFGL-----------FATLGFFAPSLY 333

  Fly   461 ------NLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSIIFVALTRSIMAEQ 519
                  :||..:...||.||..||.::..||....:.:|..|:|..|.|:.:|.:.::.......
Human   334 IIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFA 398

  Fly   520 TEWTQLMIWLSICGFFRGSALSNF------TLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLI 578
            ||:..||    .|..|.|..:...      .|...:...:||:.||.|.::..:::..:...||.
Human   399 TEFWGLM----SCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLA 459

  Fly   579 GLIRDVTDSYPICIHT-------QSVCIMI 601
            ||:.|.:..|....::       .:||:.:
Human   460 GLLVDQSKIYSRAFYSCAAGMALAAVCLAL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	16..>193	CDD:475125	41/176 (23%)
		MFS	<428..609	CDD:475125	49/198 (25%)
SLC16A6	XP_024306789.2	MFS_MCT7	43..491	CDD:340980	115/610 (19%)