DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8034 and MCH5

DIOPT Version :9

Sequence 1:	NP_573376.2	Gene:	CG8034 / 32924	FlyBaseID:	FBgn0031011	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_014951.4	Gene:	MCH5 / 854483	SGDID:	S000005833	Length:	521	Species:	Saccharomyces cerevisiae

Alignment Length:	227	Identity:	56/227 - (24%)
Similarity:	96/227 - (42%)	Gaps:	26/227 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PDGGW-GWVACFGVSLVNLATRSIEPSFGL----LFGDTLKELNVGTTGAAVIISALDVCMNFSG 70
            |:||: .||..||..|..:|...:..|.|:    |..:.|...:|.|.|....: .|.|| :.|.
Yeast   100 PEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSESVSTIGWLFSL-FLFVC-SASC 162

  Fly    71 LFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHY 135
            :..|.......:|.:.|.|::....||..|:.:|...|.:.:::::.|.|.|:..|.......||
Yeast   163 IISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHY 227

  Fly   136 FKHKRGQAVGLSMAGTAMGMLIMPQLVRILLE-------AYDFRGAVLLLAGVALN-ATVGSVLL 192
            |..:||.|:.::..|.::|.::.|.::|....       .|.|...:..|..:.|. .|:..:|:
Yeast   228 FFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILV 292

  Fly   193 QPVKWHMKEEFDDEE-----------LMCISA 213
            :....|:.|...|.|           |.|..|
Yeast   293 KERLPHVIENSKDGESRWRYILRVYILQCFDA 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	44/188 (23%)
		MFS	<437..583	CDD:119392
		MFS_1	437..>581	CDD:284993
MCH5	NP_014951.4	MFS_MCT_SLC16	106..510	CDD:340910	53/221 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I2686
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13433
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.870