DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8034 and MCH4

DIOPT Version :9

Sequence 1:	NP_573376.2	Gene:	CG8034 / 32924	FlyBaseID:	FBgn0031011	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_014522.1	Gene:	MCH4 / 854030	SGDID:	S000005479	Length:	501	Species:	Saccharomyces cerevisiae

Alignment Length:	222	Identity:	51/222 - (22%)
Similarity:	98/222 - (44%)	Gaps:	37/222 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PDGGW-GWVACFGVSLVNLATRSIEPSFGLLFGDTLKEL----------NVGTTGAAVIISALDV 64
            ||||. .|:..||      |...:.|.|||:  ::|..:          |:.::..:.|.| |.:
Yeast    90 PDGGLKAWLVVFG------AFMGLVPVFGLI--NSLGAIESYISKHQLANISSSTISWIFS-LYL 145

  Fly    65 CMNF-SGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAA 128
            .::| |.:..|..........:...|:::...||...:...|:...:..:||.:|:|.|:..:..
Yeast   146 AISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPL 210

  Fly   129 FVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATV-GSVL- 191
            ...:..:|..:||.|..:|..|.::|.::.|.::|.|.:...|:.|:.:|:.:.|...: .|||
Yeast   211 IGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLA 275

  Fly   192 -------LQP-------VKWHMKEEFD 204
                   :||       .||::...|:
Yeast   276 RERTKPVVQPFKSKAEVAKWYISSVFN 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	43/203 (21%)
		MFS	<437..583	CDD:119392
		MFS_1	437..>581	CDD:284993
MCH4	NP_014522.1	MFS_MCT_SLC16	96..490	CDD:340910	47/216 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13433
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870