Protein Alignment CG8034 and MCH2

DIOPT Version :10

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_012701.2
• Gene: MCH2 / 853659
• SGDID: S000001704
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 649
• Identity: 109/649 - (16%)
• Similarity: 186/649 - (28%)
• Gaps: 244/649 - (37%)

  Fly    11 PDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGP 75
            ||||:||.......|.|.:|......:.:.....| |.|....|:.:..:::.......|||..|
Yeast    36 PDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYL-ENNTFAGGSKLDYASIGGLAFSCGLFFAP 99

  Fly    76 ----LLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYF 136
                |...||.:.:...|.|..|..|.|.:.:.::..|..|..|:.|.|:......:...:..:|
Yeast   100 VITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWF 164

  Fly   137 KHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVL-LQPVKWHMK 200
            ::||..|.|:..||:.:|                         |:..|..:.|:| .:.|||.:.
Yeast   165 RNKRSLASGIGTAGSGLG-------------------------GIVFNLGMQSILQKRGVKWALI 204

  Fly   201 EEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHP-- 263
            .:.    ::|.|                                     |..:..:|....|.
Yeast   205 AQC----IICTS-------------------------------------LSTIALMLTRTTHQGL 228

  Fly   264 HQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLR 328
            .||.....:..:..:.::...:.:    .|                     |:.|.|.:....|.
Yeast   229 RQHKRSYKFELLDYDVLSNFAVWL----LF---------------------GFVSFAMLGYVVLL 268

  Fly   329 CRKASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTEL 393
            ...:..|.:|.|....||.:...::               ||:..|..::|...|.:
Yeast   269 YSLSDFTVSLGYTSKQGSYVSCMVS---------------VGSLLGRPIVGHIADKY-------- 310

  Fly   394 DKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTPFF 458
                                             ..|...|.|:|:       :|.:.:.|..|
Yeast   311 ---------------------------------GSLTVGMILHLV-------MAILCWAMWIP-- 333

  Fly   459 FANLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSIIFVALTRSIMAEQTEWT 523
                         |.::.                           .:|.|..|..|||.
Yeast   334 -------------CKNLA---------------------------TAIAFGLLVGSIMG------ 352

  Fly   524 QLMIWLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDS- 587
              .||.:|...            |:....|:|||..||...:..|.|.:. .|:|||....||:
Yeast   353 --TIWPTIASI------------VTRIVGLQKLPGTFGSTWIFMAAFALV-APIIGLELRSTDTN 402

  Fly   588 ----YPICIHTQSVCIMICATAWGIEYLVEYIQSRRRTADAAQLPTQDVGATTTATSDQNDVKL 647
                |...|........:....|   .|..:|.:|           .::......::|||::.|
Yeast   403 GNDYYRTAIFVGFAYFGVSLCQW---LLRGFIIAR-----------DEIAVREAYSADQNELHL 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	16..>193	CDD:475125	38/181 (21%)
		MFS	<428..609	CDD:475125	35/185 (19%)
MCH2	NP_012701.2	MFS_MCT_SLC16	41..428	CDD:340910	98/607 (16%)