DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8034 and SLC16A2

DIOPT Version :9

Sequence 1:	NP_573376.2	Gene:	CG8034 / 32924	FlyBaseID:	FBgn0031011	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_006508.2	Gene:	SLC16A2 / 6567	HGNCID:	10923	Length:	539	Species:	Homo sapiens

Alignment Length:	168	Identity:	52/168 - (30%)
Similarity:	83/168 - (49%)	Gaps:	14/168 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QPRKVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTL---KELNVGTTGAAVIISALDVCM 66
            ||    |:||:|||..|..:..|.:...|..|.|:|:...|   ||.|......|..:.||.:.|
Human    93 QP----PEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGM 153

  Fly    67 NFSGLFVGPLLKEFS----YRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSA 127
            .|   |..|::..|:    .|..|.||:.:..:||..:|..:|::....||.::.|.|...:...
Human   154 IF---FCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQP 215

  Fly   128 AFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRIL 165
            :.|.|.|||:.:.|.|.|:..||:::..:..|.|:|:|
Human   216 SLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRML 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	44/153 (29%)
		MFS	<437..583	CDD:119392
		MFS_1	437..>581	CDD:284993
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..92
		2A0113	86..513	CDD:273325	52/168 (31%)
		MFS	101..498	CDD:119392	46/156 (29%)
		DUF1564	<286..>334	CDD:284922
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	508..539
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820