Protein Alignment CG8034 and SLC16A1

DIOPT Version :9

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001159968.1
• Gene: SLC16A1 / 6566
• HGNCID: 10922
• Length: 500
• Species: Homo sapiens
• Alignment Length: 661
• Identity: 122/661 - (18%)
• Similarity: 209/661 - (31%)
• Gaps: 213/661 - (32%)

  Fly    11 PDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGP 75
            |||||||....| :.:::......|....:|...::.:...||.....||::.:.:.:.|   ||
Human    14 PDGGWGWAVVIG-AFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGG---GP 74

  Fly    76 ----LLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYF 136
                |:.::..|.|.|.|..|.|.||...|...::..:.....||.|:|:..:.:.|...:..||
Human    75 ISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYF 139

  Fly   137 KHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKE 201
            ..:|..|.||:|||:.:.:..:..|.::....:.:||:.|:|.|:.||..|...|::|:
Human   140 YKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPI------ 198

  Fly   202 EFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQH 266
                          .|:|          ..||
Human   199 --------------GPKP----------TKAG--------------------------------- 206

  Fly   267 SMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRK 331
               |:.|:.::.....|                 ||:...|.|..|
Human   207 ---KDKSKASLEKAGKS-----------------GVKKDLHDANTD------------------- 232

  Fly   332 ASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQ 396
                                                         ::|.|
Human   233 ---------------------------------------------LIGRH--------------- 237

  Fly   397 AEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTPF-FFA 460
                        .|.:|...::.....||:.:...:.||..|.|..|.:     |.:..|. |.:
Human   238 ------------PKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMF-----FGLFAPLVFLS 285

  Fly   461 NLG----YQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRT--IFLVSIIFVALTRSIMAEQ 519
            :.|    |.....||.|||.|..|:.||..:..:.:...|:.|.  .|..|::...:...:....
Human   286 SYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLS 350

  Fly   520 TEWTQLMIWLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDV 584
            |.:....::....||..|...|....|:.:....::..||.|...:.:...|:...||:|.:.|:
Human   351 TTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDM 415

  Fly   585 TDSYPICIHTQSVCIMICA----TAWGIEYLV-----------EYIQSRRRTADAAQLPTQDVGA 634
            ...|........|.::|..    ...||.|.:           :..:....:.|.|..|.:   .
Human   416 YGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNE---V 477

  Fly   635 TTTATS-DQND 644
            |..|.| ||.|
Human   478 TKAAESPDQKD 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	45/180 (25%)
		MFS	<437..583	CDD:119392	34/152 (22%)
		MFS_1	437..>581	CDD:284993	34/150 (23%)
SLC16A1	NP_001159968.1	2A0113	1..455	CDD:273325	113/623 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..500		9/38 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820