DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8034 and slc16a10

DIOPT Version :9

Sequence 1:	NP_573376.2	Gene:	CG8034 / 32924	FlyBaseID:	FBgn0031011	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_001073497.1	Gene:	slc16a10 / 566499	ZFINID:	ZDB-GENE-040724-214	Length:	505	Species:	Danio rerio

Alignment Length:	212	Identity:	56/212 - (26%)
Similarity:	98/212 - (46%)	Gaps:	29/212 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KQPRKV-APDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVI------ISA 61
            |.|.:. .|:||||||........|.:...|:.:||::|...|.|.  |:...|.:      :.:
Zfish    57 KSPEEFEPPEGGWGWVVMLASMWCNGSVFGIQNAFGIMFVYLLNEF--GSEHDADLRFKTAWVGS 119

  Fly    62 LDVCMNFSGLFVGPLLKEFS----YRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVG 122
            |.:.|.|   |..|::..|:    .|..|:.|:.:..:||..:|..||:..:..||.::...|..
Zfish   120 LSMGMIF---FCSPIVSVFTDLLGCRITAVGGAAVGCVGLLASSFVTSLGPMYFTYGIVFACGCS 181

  Fly   123 LSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGA---------VLLL 178
            .:...:.|.|.||||.:.|...|:..||:::..:.:|.::..||::......         :|:|
Zfish   182 FAYQPSLVILGHYFKRRLGLVNGIVTAGSSVFTITLPYMLSGLLKSVGLYHTLRVLAIFMFILML 246

  Fly   179 AGVALNATVGSVLLQPV 195
            ||:    |...:|.:||
Zfish   247 AGL----TYKPLLPKPV 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	47/195 (24%)
		MFS	<437..583	CDD:119392
		MFS_1	437..>581	CDD:284993
slc16a10	NP_001073497.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64		2/6 (33%)
		2A0113	56..458	CDD:273325	56/212 (26%)
		MFS	71..462	CDD:119392	49/198 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	474..505
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820