Protein Alignment CG8034 and slc16a12b

DIOPT Version :9

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001139286.1
• Gene: slc16a12b / 449947
• ZFINID: ZDB-GENE-050522-80
• Length: 488
• Species: Danio rerio
• Alignment Length: 634
• Identity: 135/634 - (21%)
• Similarity: 220/634 - (34%)
• Gaps: 213/634 - (33%)

  Fly    11 PDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGP 75
            |||||||:...|..:|.:.||::.....:.|.:.........:|.|.|.|.:| |.......:|.
Zfish    24 PDGGWGWMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYSGTAWIHSLVD-CTTMLCAPLGS 87

  Fly    76 LL-KEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYFKHK 139
            |: .:.|.|...|.|..|..:||.|:|.|||:.::.:|..::.|:|..|..:.|...:..||..:
Zfish    88 LIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLGFALCYTPAIAMVGIYFCER 152

  Fly   140 RGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFD 204
            :..|.|::|:|:.:|..|:..:|::|:|.|.:|||:|:|.|..||..|...||:|:  .:|||
Zfish   153 KALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPI--ILKEE-- 213

  Fly   205 DEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMR 269
                   .|.|.|                     |..|.|
Zfish   214 -------EACPLP---------------------VDSECG------------------------- 225

  Fly   270 KNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASV 334
              ||              .|.||.                   :||.|..|..:|.| ||.::..
Zfish   226 --YS--------------VKPPTL-------------------NGGPTRSAASDAKQ-RCFQSMQ 254

  Fly   335 TSNLSYM-DFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAE 398
            ..:...| ||                                :||.|
Zfish   255 EYHFLLMPDF--------------------------------LVLAG------------------ 269

  Fly   399 AAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTPFFF-ANL 462
                                              .||.|..|.|:.:|      .:.|:.. ..:
Zfish   270 ----------------------------------SFLLLASGCSLPFV------YLVPYALDVGV 294

  Fly   463 GYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKK-RTI---FLVSI-----IFVALTRSIMAE 518
            |:|  ..||.:||..:.||...|....:.||..:|| |.|   |.|.:     :|:.|.|:
Zfish   295 GHQ--HAAFLMSILGVIDIVGNITFGWLTDRRCLKKYRNICYMFAVGMEGLCCLFIPLLRT---- 353

  Fly   519 QTEWTQLMIWL----SICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIG 579
                   .:||    .:.|:|.|:.::...:..|:....:.|.||.|......|:..:...|:.|
Zfish   354 -------FVWLVPFSVLYGYFDGAYVALIPVVTSDVVGRQYLSSALGVVYFLHAVPYLVSPPIGG 411

  Fly   580 LIRDVTDSYPICIHTQSVCIMICATAWGIEYLVEYIQSRRRTADAAQLP 628
            .:.|.|.:|..........::..:.......::.|.|..::....:::|
Zfish   412 WLVDTTGTYTATFFLSGFALISSSLLLFSVAIIRYCQRNQKKNSLSKIP 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	54/177 (31%)
		MFS	<437..583	CDD:119392	38/159 (24%)
		MFS_1	437..>581	CDD:284993	38/157 (24%)
slc16a12b	NP_001139286.1	MFS	33..430	CDD:119392	125/593 (21%)
		MFS_1	37..407	CDD:284993	119/566 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010