Protein Alignment CG8034 and SLC16A12

DIOPT Version :9

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_998771.3
• Gene: SLC16A12 / 387700
• HGNCID: 23094
• Length: 516
• Species: Homo sapiens
• Alignment Length: 595
• Identity: 116/595 - (19%)
• Similarity: 196/595 - (32%)
• Gaps: 194/595 - (32%)

  Fly    11 PDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGP 75
            |||||||:...|..||.:.||::.....:.|.:............|.|.|.:| |:......:|.
Human    43 PDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVD-CVTMLCAPLGS 106

  Fly    76 LLKEFSYRKVAI-AGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYFKHK 139
            ::......:|.| .|.||...||.|:|.|||:.|:..|..|:.|:|..|..|.|...:..||..:
Human   107 VVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRR 171

  Fly   140 RGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFD 204
            :..|.|::|:|:.:|..|:..:|::|:|.:.:|||:|:|.|..||..|...|::|:.  :||:.
Human   172 KALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPIT--LKEDH- 233

  Fly   205 DEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMR 269
                      .||:..              .|.:..|||              ..:..|:. |:.
Human   234 ----------TTPEQN--------------HVCRTQKED--------------IKRVSPYS-SLT 259

  Fly   270 KNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASV 334
            |.:::                                                  |.|.|.....
Human   260 KEWAQ--------------------------------------------------TCLCCCLQQE 274

  Fly   335 TSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEA 399
            .|.|...||.  :|.|.:
Human   275 YSFLLMSDFV--VLAVSV----------------------------------------------- 290

  Fly   400 AAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTPFFFANLGY 464
                                               |.:.:|.|..:|      .:.|:.. ::|.
Human   291 -----------------------------------LFMAYGCSPLFV------YLVPYAL-SVGV 313

  Fly   465 QKTDVAFCLSITAITDIAARIVLPPIFDRTTIK--KRTIFLVSIIFVALTRSIMAEQTEWTQLMI 527
            .....||.:||..:.||...|....:.||..:|  :...:|.::....|....:........|:.
Human   314 SHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVP 378

  Fly   528 WLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDSYPICI 592
            :....|:|.|:.::...:..:|......|.||.|......|:..:...|:.|.:.|.|.||
Human   379 FSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSY---- 439

  Fly   593 HTQSVCIMIC 602
               :...::|
Human   440 ---TAAFLLC 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	54/177 (31%)
		MFS	<437..583	CDD:119392	29/147 (20%)
		MFS_1	437..>581	CDD:284993	29/145 (20%)
SLC16A12	NP_998771.3	2A0111	42..481	CDD:331689	116/595 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920