Protein Alignment CG8034 and chk

DIOPT Version :10

• Sequence 1: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_610230.3
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Alignment Length: 804
• Identity: 167/804 - (20%)
• Similarity: 294/804 - (36%)
• Gaps: 220/804 - (27%)

  Fly     4 KQPRKVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNF 68
            |.|:  .||||:|||..|...:|:|....:..||||:..:.|:.....|:..|.|.|     :.|
  Fly   128 KTPK--MPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISS-----LFF 185

  Fly    69 S-GLFVGP----LLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAA 128
            | .|.:||    |:.::..||:.|.|.::...|.||:|...|:..::.|:.:|:|:|:|:....|
  Fly   186 SVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTA 250

  Fly   129 FVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQ 193
            .|::..:|..||..|.|:..:||.:|..:..:|...|:|:|.:|||.|:|.|..|||.|...|::
  Fly   251 VVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMR 315

  Fly   194 PVKWHMKEE-----------FDDEELMCISALP-------TPQPQL----TVGGAGGAASAGAPV 236
            ...|.::|.           |.:.. :|:..:.       |.:..|    |............|:
  Fly   316 DPDWLIEENRLESRSQSVTTFSNSS-VCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPL 379

  Fly   237 FKVIKE-----------DGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKR 290
            ...:|.           ...|.|::.|:.:|       .:.|:|....|.|           |.|
  Fly   380 DSALKRYRSEIFLPTFLSTQELDSICEVKSL-------SRRSLRHKEGEEA-----------PSR 426

  Fly   291 PTFPRIMSLAGV---QSAAHGAGGDS--GGYTSQAEVNATQLRCRKASV-TSNLSYMDFTGSILQ 349
            .....:.|.||.   .:|..|:..|:  ||...:|...|.  :...||: |.:.|....||....
  Fly   427 ENLLSMSSGAGAYPPSTAVIGSPDDTLMGGIAHEAAEEAK--KAYLASIETLSPSEKRSTGRTPN 489

  Fly   350 VHLNTGDDEF------------EQNDRELRRVGTATGSIVLGGHRDSFI---------------- 386
            ..|.:.|:.:            .:|....:....:..::.:.|.|.:.:
  Fly   490 GSLRSSDEGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDET 554

  Fly   387 --------KMKPT-------ELDKQAEAA---AALDE----EAKKKAKKPGF----WRRFADLLD 425
                    :::||       |....:|.|   |.||.    ....::|||..    .||...:.:
  Fly   555 FALLEPSRRIRPTVIAIPEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRN 619

  Fly   426 IDMLKD----------------------------------------------------------- 431
            .:.|||
  Fly   620 SNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFD 684

  Fly   432 -KMFLNL---LFGLS-----IFYVAEMNFKMVTPFFFANLGYQKTDVAFCLSITAITDIAARIVL 487
             .:||::   ||.||     |:::...   :..|.:.....|..:..|..:|...|......|.|
  Fly   685 FSLFLDMKFALFNLSTLFLFIWFIIPY---LYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGL 746

  Fly   488 PPIFDRTTIKKRTIFLV-------SIIFVALTRSIMAEQTEWTQLMIWLSICGFFRGSALSNFTL 545
            ..:.|.:.:.....:.:       |:.|:.|.      .|.:..||:...|.||   :..|:|:.
  Fly   747 GYLGDLSWMNINICYSLCMLVCGASVFFMPLL------ITNYMGLMVMCVIFGF---TFASSFSF 802

  Fly   546 TVSEYCS---LEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDSYPICIHTQSVCIMICATAWG 607
            |.|...|   |:....|:|..|:.:.:.:|...|:.|:|.:.|..:....:...:.|.:....
  Fly   803 TPSILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVC-- 865

  Fly   608 IEYLVEYIQSRR-RTADAAQLPTQ 630
             .||:|:.:.:. :.:|:..|.|:
  Fly   866 -SYLIEFCEKKAPKESDSDVLETK 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	16..>193	CDD:475125	60/181 (33%)
		MFS	<428..609	CDD:475125	42/258 (16%)
chk	NP_610230.3	MFS_MCT_SLC16	138..>315	CDD:340910	60/181 (33%)
		MFS	<687..869	CDD:475125	40/196 (20%)