DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8034 and SLC16A13

DIOPT Version :9

Sequence 1:	NP_573376.2	Gene:	CG8034 / 32924	FlyBaseID:	FBgn0031011	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_963860.1	Gene:	SLC16A13 / 201232	HGNCID:	31037	Length:	426	Species:	Homo sapiens

Alignment Length:	219	Identity:	61/219 - (27%)
Similarity:	103/219 - (47%)	Gaps:	17/219 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RKVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVI--ISALDVCMNFS 69
            |...||||||||........:.....:..|||:.|.:.:....   ..||.:  |:::.:.:...
Human     4 RTEPPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFE---EQAARVSWIASIGIAVQQF 65

  Fly    70 GLFVGPLLK-EFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALN 133
            |..||..|. :|..|.|.:.|.:|..||:.|.|.|||:.|:..:..:::|.|..|:.:.....|:
Human    66 GSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLS 130

  Fly   134 HYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWH 198
            .||..:|..|.||::.|..:.........:.||..|.:||::||::.::|:......||:|..
Human   131 CYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPS-- 193

  Fly   199 MKEEFDDEELMCISALPTPQPQLT 222
            :.|:         .|:..|:.|||
Human   194 LAED---------PAVGGPRAQLT 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	46/179 (26%)
		MFS	<437..583	CDD:119392
		MFS_1	437..>581	CDD:284993
SLC16A13	NP_963860.1	MFS	14..392	CDD:119392	54/209 (26%)
		MFS_1	21..357	CDD:284993	52/202 (26%)
		DUF3172	369..>419	CDD:288260
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820