DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8034 and SLC16A10

DIOPT Version :9

Sequence 1:	NP_573376.2	Gene:	CG8034 / 32924	FlyBaseID:	FBgn0031011	Length:	647	Species:	Drosophila melanogaster
Sequence 2:	NP_061063.2	Gene:	SLC16A10 / 117247	HGNCID:	17027	Length:	515	Species:	Homo sapiens

Alignment Length:	290	Identity:	67/290 - (23%)
Similarity:	107/290 - (36%)	Gaps:	88/290 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASKQPRK--VAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELN-------------VG 51
            |:.:|.:  ..|:|||||:........|.:...|:.:.|:||...|:...             ||
Human    54 ATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVG 118

  Fly    52 TTGAAVIISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVI 116
            :....:|.....:...|:.|        |..||.|:.|:.:..:||..:|..:|:..:..||.:|
Human   119 SLSMGMIFFCCPIVSVFTDL--------FGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGII 175

  Fly   117 NGIGVGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEA----YDFRGA--- 174
            ...|...:...:.|.|.||||.:.|...|:..||:::..:::|.|:|:|:::    |..|..
Human   176 FACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIF 240

  Fly   175 --VLLLAGVALNATV-----------GSVLLQPVK--------------------W--------- 197
              ||.|||.......           ||.|....|                    |
Human   241 MFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPLALF 305

  Fly   198 -----------HMKEEFDDEE-----LMCI 211
                       |:.|.|.||:     ||||
Human   306 GYFVPYVHLMKHVNERFQDEKNKEVVLMCI 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8034	NP_573376.2	MFS	20..>197	CDD:119392	49/229 (21%)
		MFS	<437..583	CDD:119392
		MFS_1	437..>581	CDD:284993
SLC16A10	NP_061063.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..48
		2A0113	67..487	CDD:273325	64/277 (23%)
		MFS	71..470	CDD:119392	60/273 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820