DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8028 and Slc16a5

DIOPT Version :9

Sequence 1:	NP_001097031.2	Gene:	CG8028 / 32923	FlyBaseID:	FBgn0031010	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001103038.1	Gene:	Slc16a5 / 690212	RGDID:	1582896	Length:	466	Species:	Rattus norvegicus

Alignment Length:	544	Identity:	121/544 - (22%)
Similarity:	206/544 - (37%)	Gaps:	116/544 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LEAPDGGWGILVCIGMALPFTSAL-AALPS-FGLVFGEFLKSIGAETSAMAIITSAFFSSMSFAG 93
            ||..||.|..:|.:...:  |.|| ...|| .|:.|.:..:...|..|..:...|...:.:...|
  Rat     5 LEQADGRWAWVVLLASLV--TQALTVGFPSCIGVFFTDLQRDFQASNSETSWFPSIMGAMLHCGG 67

  Fly    94 LFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFNHY 158
            .....|.:|||.|...:.||:|..||.....|:.|.:||.:...::.|........:..|....|
  Rat    68 PLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLGMCFSFQSSITVVGLY 132

  Fly   159 FVKNRVMWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCLLILTGLNAHAVFGMLVMHPVEWHMR 223
            ||:.|.:..:.|...|.:|..|:|::.:.|:...|:||..||..|:..|......::.||..:
  Rat   133 FVRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPVATN-- 195

  Fly   224 RVPIQPEEQEELKELSPTVVIRVQPETP----LKATREEPNFHTADPGARKLSHAEEQMLKVLSS 284
               :.||.:|:|  |.|       |:||    |........::.|      .......|:..:..
  Rat   196 ---VDPEPKEDL--LLP-------PKTPTRSCLATCVSTIQYYLA------FDILRHNMVFCIYV 242

  Fly   285 RASSITSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIVDFLDLT 349
            ..::..:|| :|.|.:.  ..|..||                     |..::.|...::..:.
  Rat   243 TGATWMTLG-FSLPHIF--LVPYAMH---------------------HGMEEYWAAMLMSIVG-- 281

  Fly   350 LLKKPIFVNIVLGITFALYSDITFFTMQPVYLFELGYSRPDTATIIAIGAAADLASRIFLAITAV 414
                  |.||.|                          || .|.::| |..:..|.|.:|...|:
  Rat   282 ------FCNIFL--------------------------RP-VAGMLA-GRKSLAAYRKYLFAVAI 312

  Fly   415 CIQVPSRYIYLAGAVFTVFARFAFNGITQFVGMACITAVIGFLRTWLHVPLPLVFADYLPKERFA 479
            .|...:..|....|.|.|...:.   :...:.| |.|.::.|          .|..|.:|.:||.
  Rat   313 LINGLTNLICTVSADFRVLLGYC---LVYSLSM-CGTGILVF----------QVLMDIVPMDRFP 363

  Fly   480 TGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHILNGFMI-----LCAAPWVLEVLIVKFRR 539
            :..|||..:.|....:..|:.|.:.|.|.::.:||::.:|.:|     :....:|.|..: |..|
  Rat   364 SALGLFTILCGMGSLISPPLAGLLLDTTNNFNYVFYMSSGLLISASLFMGVGFYVAEKKL-KQDR 427

  Fly   540 RNKIE--------RNNVDHEDVDN 555
            :.|:|        ::::..||.|:
  Rat   428 QAKMEDATSEITSKHSLTSEDKDS 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS	40..>215	CDD:119392	45/176 (26%)
Slc16a5	NP_001103038.1	2A0113	1..432	CDD:273325	117/523 (22%)
Slc16a5	NP_001103038.1	MFS	32..412	CDD:119392	102/473 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920