Protein Alignment CG8028 and SLC16A1

DIOPT Version :9

• Sequence 1: NP_001097031.2
• Gene: CG8028 / 32923
• FlyBaseID: FBgn0031010
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001159968.1
• Gene: SLC16A1 / 6566
• HGNCID: 10922
• Length: 500
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 129/556 - (23%)
• Similarity: 207/556 - (37%)
• Gaps: 119/556 - (21%)

  Fly    29 YTLEAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKSIGAETSAMAIITSAFFSSMSFAG 93
            ||  .||||||..|.||..:....:.|...|..:.|.|......|.||.::.|:|...:.|...|
Human    11 YT--PPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGG 73

  Fly    94 LFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFNHY 158
            ..|..|..::|.|.|.:.||.|...|.....|..:...|.:...|:.|......:....|....|
Human    74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKY 138

  Fly   159 FVKNRVMWMSFAQTLIGLGSMLYPIVM----QKLMSWYGFRGCLLILTGLNAH-AVFGMLVMHPV 218
            |.|.|.:    |..|...||.::...:    |.....:|:||..|||.||..: .|.|.|
Human   139 FYKRRPL----ANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGAL----- 194

  Fly   219 EWHMRRVPIQPEEQEELKELSPTVVIRVQPETPLKATREEPNFHTADPGARKLSHAEEQMLKVLS 283
               ||  ||.|:..:..|:.|             ||:.|:    ....|.:|..|
Human   195 ---MR--PIGPKPTKAGKDKS-------------KASLEK----AGKSGVKKDLH---------- 227

  Fly   284 SRASSITSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIVDFLDL 348
                               ||:..::     .|.|.             ..|:|..:||..||||
Human   228 -------------------DANTDLI-----GRHPK-------------QEKRSVFQTINQFLDL 255

  Fly   349 TLLKKPIFV-----NIVLGITFALYSDITFFTMQPVYLFELGYSRPDTATIIAIGAAADLASRIF 408
            ||.....|:     |:::  .|.|::.:.|.:.   |.....||...:|.:::|.|..|:.:|..
Human   256 TLFTHRGFLLYLSGNVIM--FFGLFAPLVFLSS---YGKSQHYSSEKSAFLLSILAFVDMVARPS 315

  Fly   409 LAITAVCIQVPSR--YIYLAGAVFTVFARFAFNGI--------TQFVGMACITAVIGFLRTWLHV 463
            :.:.|....:..|  |.:.|..|        .||:        |.:||........||...||..
Human   316 MGLVANTKPIRPRIQYFFAASVV--------ANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSS 372

  Fly   464 PLPLVFADYLPKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHILNGFMILCAAPW 528
            .|.....|.:..:||::..||...::...:.|..|::|.:.|...||.:.:......:|:.....
Human   373 VLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYL 437

  Fly   529 VLEV-----LIVKFRRRNKIERNNVDHE-DVDNQGR 558
            .:.:     |:.|.::.|:.::.:.:.| .:|..|:
Human   438 FIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGK 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS	40..>215	CDD:119392	48/179 (27%)
SLC16A1	NP_001159968.1	2A0113	1..455	CDD:273325	125/536 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..500		4/20 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7473
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820