DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8028 and slc16a6b

DIOPT Version :9

Sequence 1:	NP_001097031.2	Gene:	CG8028 / 32923	FlyBaseID:	FBgn0031010	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001352167.1	Gene:	slc16a6b / 561766	ZFINID:	ZDB-GENE-110208-3	Length:	527	Species:	Danio rerio

Alignment Length:	548	Identity:	123/548 - (22%)
Similarity:	217/548 - (39%)	Gaps:	84/548 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 EAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKSIGAETSAMAIITSAFFSSMSFAGLFS 96
            |.||||||.:|..............:.:||:...:.:.......|.::...|.....|:|....|
Zfish    15 EVPDGGWGWMVAAAFFFVEVFTYGIIKTFGIFLQDLMTEFHETNSRVSWAVSICVFVMAFTAPLS 79

  Fly    97 GSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFNHYFVK 161
            ..|..|||.|.|.:.||.|..|||.......|...:.:...:|.|..:.|......|..:.||.|
Zfish    80 TLLSNRFGHRPVVMVGGFLISLGTITTALTQSIDEMYITMGIVAGLGYCLTFLPTVTILSQYFSK 144

  Fly   162 NRVMWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCLLILTGLNAHAVFGMLVMHPVEWHMRRVP 226
            .|.:..|.|.|......:.:...|..|....|:|.||:::..|.|..:....::.|       :.
Zfish   145 RRSLVTSIASTGECFSMLAFAPAMNALKEQIGWRYCLMVIGVLQASIIVCGALLKP-------IV 202

  Fly   227 IQPEEQEELKELSPTVVI--RVQPETPLKATREEPNFHTADPGARKLSHAEEQMLKVLSSRASSI 289
            |:|:...:....||..|:  :...|.....|    :|.:.|.|.:.:|.::..:.|....:..
Zfish   203 IKPKPATQEASTSPLKVLDSKYDAENEFTCT----SFDSVDSGVQSISSSQVNLAKEQQKKEE-- 261

  Fly   290 TSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIVDFLDLTLLKKP 354
                        ...||:.  .|:..:..|:::                 ||  ..||.::|:..
Zfish   262 ------------EGESPET--PLKQKQEDSSVS-----------------RT--KLLDFSVLRDA 293

  Fly   355 IFVNIVLGITFALYSDITFFTMQPVYLFEL----GYSRPDTATIIAIGAAADLASRIFLAITAVC 415
            .|....|   |.|::.:.||..| :|:.:|    |.|:.....:::..|.|::..|  |::..|.
Zfish   294 SFNCYAL---FGLFATLGFFAPQ-IYIIQLSVSRGVSQKSATYMLSAMAVAEIGGR--LSMGWVL 352

  Fly   416 IQVPSRYIYLAGAVFTVF---ARFAFNGITQFVGMACITAVIGFLRTWL---HVPLPLVFADYLP 474
            .:.|.|.||:. .:.||.   ....|..:::|.|:...:.:.|||...:   |:|: |...|.:.
Zfish   353 NRKPIRKIYIL-LICTVLLCPVLVVFTFVSEFWGLMSCSCLYGFLLGTVASSHIPM-LAEDDVIG 415

  Fly   475 KERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHILNGFMILCAAPWVLEVLIVK--- 536
            .:|.::..|:::.||..|.....|:.||:.|:|.:|...|:       .|||...:..|.:.
Zfish   416 IQRMSSAVGVYVCIQSFAGLAGPPLGGFLVDQTNNYGSAFY-------SCAAGMGVGALFLGLVR 473

  Fly   537 -------FRRRNKIERNNVDHEDVDNQG 557
                   |.:|.:.::.:.| .|..:||
Zfish   474 PAKTGLCFGKRKRKDQQSAD-RDASSQG 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS	40..>215	CDD:119392	40/174 (23%)
slc16a6b	NP_001352167.1	2A0111	17..512	CDD:331689	122/546 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920