Protein Alignment CG8028 and SLC16A12

DIOPT Version :9

• Sequence 1: NP_001097031.2
• Gene: CG8028 / 32923
• FlyBaseID: FBgn0031010
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_998771.3
• Gene: SLC16A12 / 387700
• HGNCID: 23094
• Length: 516
• Species: Homo sapiens
• Alignment Length: 565
• Identity: 118/565 - (20%)
• Similarity: 196/565 - (34%)
• Gaps: 133/565 - (23%)

  Fly     6 IVWLTIEHRLQSRPAYQMKKSKSYTLEAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKS 70
            |.||..:...:.:.....|.:::.:...||||||.::..|..|......|......:.|.||...
Human    15 ITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTY 79

  Fly    71 IGAETSAMAIITSAF-FSSMSFAGLFSGSLFQRFGMRQVGV-TGGILYFLGTGMQLFATSTLHLI 133
            ...:.:..|.|.|.. ..:|..|.|  ||:.......|||: .||:|...|..:..||||..||.
Human    80 FTQDYAQTAWIHSIVDCVTMLCAPL--GSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLY 142

  Fly   134 MAFSVVQGFAFGLMVPTCYTTFNHYFVKNRVMWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCL 198
            :...|:.|..|.|...........||.:.:.:....|.:..|:|:.:...|:|.|:..:.:||.|
Human   143 LTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGAL 207

  Fly   199 LILTG--LNAHAVFGMLVMHPVEWHMRRVPIQPEEQEELKELSPTVVIRVQPETPLKATREEPNF 261
            |||.|  ||. .|.|.| |.|:               .|||                       .
Human   208 LILGGFVLNL-CVCGAL-MRPI---------------TLKE-----------------------D 232

  Fly   262 HTADPGARKLSHAEEQMLKVLSSRASSITSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASG 326
            ||                                         :|:..|..:|.:....
Human   233 HT-----------------------------------------TPEQNHVCRTQKEDIK------ 250

  Fly   327 AVAPAHATKKSWVRTIVDFL---DLTLLKKPIFVNIVLGITFALYSDITFFTMQPVYLFELGYSR 388
            .|:|..:..|.|.:|.:...   :.:.|....||.:.:.:.|..|.....|.....|...:|.|.
Human   251 RVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSH 315

  Fly   389 PDTATIIAIGAAADLASRI-FLAIT-AVCIQVPSRYIYLAGAVFTVFARFAFNGITQFVGM---- 447
            ...|.:::|....|:...| |..:| ..|::   .|.|    |..:||          |||
Human   316 QQAAFLMSILGVIDIIGNITFGWLTDRRCLK---NYQY----VCYLFA----------VGMDGLC 363

  Fly   448 -ACI------------TAVIGFLRTWLHVPLPLVFADYLPKERFATGYGLFMFIQGNAMFLIGPI 499
             .|:            :...|:........:|:|..:.:.....::..|:..|:......:..||
Human   364 YLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPI 428

  Fly   500 VGFIRDKTRDYIFVFHILNGFMILCAAPWVLEVLIVKFRRRNKIE 544
            .|.:.|.|..|...| :|.||.::.::..:....::|..|:.:::
Human   429 AGRLVDTTGSYTAAF-LLCGFSMIFSSVLLGFARLIKRMRKTQLQ 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS	40..>215	CDD:119392	51/178 (29%)
SLC16A12	NP_998771.3	2A0111	42..481	CDD:331689	114/538 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920