Protein Alignment CG8028 and chk

DIOPT Version :10

• Sequence 1: NP_001097031.2
• Gene: CG8028 / 32923
• FlyBaseID: FBgn0031010
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_610230.3
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Alignment Length: 770
• Identity: 149/770 - (19%)
• Similarity: 243/770 - (31%)
• Gaps: 287/770 - (37%)

  Fly    16 QSRPAYQMKKSKSYTLEAPDGGWGILVCIGMALPFTSALAALP------SFGLVFGEFLKSIGAE 74
            :|..:.....::..|.:.||||:|.:|.      |.|.:.:|.      ||||:..|.|:..|..
  Fly   115 ESGDSIDSSSTEKKTPKMPDGGYGWVVV------FASLVVSLIADGLSFSFGLINVELLEYFGES 173

  Fly    75 TSAMAIITSAFFSSMSFAGLFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVV 139
            ||..|.|:|.|||.....|....:|..::|.|::.:.||::...|..:..|..|...|::.|.::
  Fly   174 TSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGII 238

  Fly   140 QGFAFGLMVPTCYTTFNHYFVKNRVMWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCLLILTG- 203
            .|...|:...|...:...:|.|.|........:..|:|:.:|..:...|:..||:||..|||.|
  Fly   239 SGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGT 303

  Fly   204 -LNAHAVFGMLVMHPVEWHMRRVPIQPEEQ------------EELKELSPTVVIR---------- 245
             ||| .|.|.|:..| :|.:....::...|            ||:|:|..|.:.:
  Fly   304 MLNA-CVCGALMRDP-DWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTK 366

  Fly   246 ------VQPETP----LKATREE---PNFHTADP----------GARKLSHAE-------EQMLK 280
                  .|.:.|    ||..|.|   |.|.:...          ..|.|.|.|       |.:|.
  Fly   367 NNTEANQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLS 431

  Fly   281 VLS-------------------------------------------------------------- 283
            :.|
  Fly   432 MSSGAGAYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSD 496

  Fly   284 ------SRASSITSL------GNWSGPVVVS-----------DASPQMMHS----------LQTS 315
                  ..|||..||      ...:.|.:.:           |...:.||.          |:.|
  Fly   497 EGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPS 561

  Fly   316 R--RPSTIA--GASGAVAPAHATKKSWVRTIVDFLDLTLLKKPI--------------------- 355
            |  ||:.||  ....:|....||:::.:.:|.....|:..|||.
  Fly   562 RRIRPTVIAIPEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDM 626

  Fly   356 ------------------------------------------------FVNIVLGI-TFALYSDI 371
                                                            ||:.:..| .|:|:.|:
  Fly   627 RIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDM 691

  Fly   372 TF--FTMQPVYLF-----------------------------ELGYSRPDTATIIAIGAAADLAS 405
            .|  |.:..::||                             ::|.::  |..:|.:|...||:.
  Fly   692 KFALFNLSTLFLFIWFIIPYLYLPDYMKQYKYDVSQSAELISDVGIAQ--TVGMIGLGYLGDLSW 754

  Fly   406 RIFLAITAVCIQVPSRYIYLAGAVFTVFARFAFNGITQFVGMACITAVIGFLRTWLHVPLPLVFA 470
            .......::|:.|....::....:           ||.::|:..:..:.||.........|.:..
  Fly   755 MNINICYSLCMLVCGASVFFMPLL-----------ITNYMGLMVMCVIFGFTFASSFSFTPSILV 808

  Fly   471 DYLPKERFATGYGLFMFIQGNAMFLIGPIVGFIR------DKTRDYIFVFHILNG 519
            ..:..:.|...|||.:.:||..|....||.|.|.      |.|..|..:|..|:|
  Fly   809 SIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSG 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS_MCT_SLC16	39..531	CDD:340910	143/747 (19%)
chk	NP_610230.3	MFS_MCT_SLC16	138..>315	CDD:340910	55/183 (30%)
		MFS	<687..869	CDD:475125	37/190 (19%)