DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8028 and slc16a3b

DIOPT Version :9

Sequence 1:	NP_001097031.2	Gene:	CG8028 / 32923	FlyBaseID:	FBgn0031010	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_997873.1	Gene:	slc16a3b / 327276	ZFINID:	ZDB-GENE-030131-5487	Length:	508	Species:	Danio rerio

Alignment Length:	559	Identity:	127/559 - (22%)
Similarity:	210/559 - (37%)	Gaps:	151/559 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LEAPDGGWGILVCIGMALPFTSALAALP-SFGLVFGEFLKSIGAETSAMAIITSAFFSSMSFAGL 94
            ::|||||||..|..|..: .|....|.| :..:.|.|.::..|...|..|.|:|...:.:...|.
Zfish    13 VKAPDGGWGWAVLFGCFI-ITGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLAMLYGTGP 76

  Fly    95 FSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFNHYF 159
            ....|..|||.|.|.:.||:...||..:..|||:.:|:.:...|:.|....|.........|.||
Zfish    77 LCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLGLALNFQPSLIMLNRYF 141

  Fly   160 VKNRVMWMSFAQTLIGLGSMLYPIVM-------QKLMSWYGFRGCLLILTGLNAHAVFGMLVMHP 217
            .:.|.:    |..|...||   |:.:       |.|...||:||..|||.||..:......:|.|
Zfish   142 SEKRPL----ANGLAAAGS---PVALCCLSPLGQVLQYKYGWRGGFLILGGLLLNCCACGALMRP 199

  Fly   218 VEWHMRRVPIQPEEQEELKELSPTVVIRVQPETPLKATREEPNFHT----ADPGARKLSHAEEQM 278
            :        :.|::..|::|         :|    |.|:.:|....    .|.|.
Zfish   200 L--------LAPKKTSEVEE---------KP----KETKPKPKLLDFTVFKDRGF---------- 233

  Fly   279 LKVLSSRASSITSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIV 343
              ::.:.|:||..||.:..||.|...:.::.:                     ..||.:.:.||:
Zfish   234 --LIYTIAASIMVLGLFVPPVFVVSYAKELGN---------------------EDTKSALLLTIL 275

  Fly   344 DFLDLTLLKKPIFVNIVLGITFALYSDITFFTMQPVYLFELGYSRPDTATIIAIGAAADLASRIF 408
            .|:|  :..:|         |..:.:.:.:...:.||||.........|.|:. ..|.|.||.:
Zfish   276 GFID--IFARP---------TSGIIAGLKWVRPRCVYLFSFAMIFNGIADILG-SFAKDYASLV- 327

  Fly   409 LAITAVCIQVPSRYIYLAGAVFTVFARFAFN--GITQFVGMACITAVIGFLRTWLHVPLPLVFAD 471
                                ||.:|...::.  |..||   ..:.|::|
Zfish   328 --------------------VFCIFFGISYGMVGALQF---EVLMAIVG---------------- 353

  Fly   472 YLPKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHILNGFMILCAAPWVLEVLIVK 536
               .|:|::..||.:.::..|:.:..|..|.:.|.|::|::||.:....::|.|.  ||.:..:.
Zfish   354 ---TEKFSSAIGLVLLVEAIAVLVGPPGAGRLLDATKNYMYVFMLAGCEVVLSAL--VLAICNLL 413

  Fly   537 FRRRN--------KIER----------NNVDHEDVDNQG 557
            |.:|.        |:|.          |....:|.||.|
Zfish   414 FIKRKPQQPDPPAKMEMAITETEMEELNKAPKDDQDNGG 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS	40..>215	CDD:119392	50/182 (27%)
slc16a3b	NP_997873.1	MFS	22..410	CDD:119392	111/506 (22%)
slc16a3b	NP_997873.1	MFS_1	25..376	CDD:284993	99/467 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.010