DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8028 and Slc16a7

DIOPT Version :9

Sequence 1:	NP_001097031.2	Gene:	CG8028 / 32923	FlyBaseID:	FBgn0031010	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_058998.2	Gene:	Slc16a7 / 29735	RGDID:	3691	Length:	489	Species:	Rattus norvegicus

Alignment Length:	556	Identity:	115/556 - (20%)
Similarity:	193/556 - (34%)	Gaps:	172/556 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PDGGWG-ILVC-----IGMALPFTSALAALPSFGLVFGEFLKSIGAETSA-MAIITSAFFSSMSF 91
            |||||| ::||     ||.:..|..|:.       ||...:|.|...||: :|.|:|...:.|..
  Rat    20 PDGGWGWVVVCASFISIGFSYAFPKAVT-------VFFNDIKDIFKTTSSQIAWISSIMLAVMYA 77

  Fly    92 AGLFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFN 156
            .|..|..|...:|.|.|.:.||:|...|..:..|::|.:.|.:....:.|......:....|...
  Rat    78 GGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFNLQPALTIIG 142

  Fly   157 HYFVKNRVMWMSFAQTLIGLGSMLYPIVM----QKLMSWYGFRGCLLILTGLNAHAVFGMLVMHP 217
            .||.:.|.:...||..    ||.::...:    |.|.:.||::|..|||..:..|:.....:|.|
  Rat   143 KYFYRKRPLANGFAMA----GSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRP 203

  Fly   218 VEWHMRRVPIQPEEQEELKELSPTVVIRVQPETPLKATREEPNFHTADPGARKLSHAEEQMLKVL 282
            |                                              .|..|    |.:...||.
  Rat   204 V----------------------------------------------GPSPR----AAKSKSKVG 218

  Fly   283 SSRASSITSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIVDFLD 347
            |.:.||...|                                         :|.|....|..|||
  Rat   219 SRQDSSTKRL-----------------------------------------SKVSTAEKINRFLD 242

  Fly   348 LTLLKKPIFV-----NIVLGITFALYSDITFFTMQPVYLFELGYSRPDTATIIAIGAAADLASR- 406
            ..|.....|:     |:||.:  .:::.|.|  :.| |..:.|....::|.::::.|..|:.:|
  Rat   243 FGLFTHRGFLIYLSGNVVLFL--GMFAPIIF--LAP-YAKDKGVDDYNSAFLLSVMAFTDMFARP 302

  Fly   407 --------------------IFLAITAVC-IQVPSRYIYLAGAVFTVFARFAFNGITQFVGMACI 450
                                :.:..|.:| :..|..:.|.|..|:.:|....|..|:..: ..|:
  Rat   303 SVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLL-FECL 366

  Fly   451 TAVIGFLRTWLHVPLPLVFADYLPKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFH 515
            ...:|                   ..||::..||...::...:....|:.|.:.|.|..|.:::
  Rat   367 MDQVG-------------------ASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLY- 411

  Fly   516 ILNGFMILCAAPWVLEV------LIVKFRRRNKIER 545
            |.:|.::|.:..::|..      |:.|.|:|.|..|
  Rat   412 IASGIVVLSSGIYLLICNAINYRLLEKERKREKARR 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS	40..>215	CDD:119392	47/184 (26%)
Slc16a7	NP_058998.2	2A0113	21..436	CDD:273325	108/542 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..227		8/24 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	441..489		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920