DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8028 and Slc16a1

DIOPT Version :9

Sequence 1:	NP_001097031.2	Gene:	CG8028 / 32923	FlyBaseID:	FBgn0031010	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_036848.1	Gene:	Slc16a1 / 25027	RGDID:	3690	Length:	494	Species:	Rattus norvegicus

Alignment Length:	561	Identity:	128/561 - (22%)
Similarity:	204/561 - (36%)	Gaps:	128/561 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 YTLEAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKSIGAETSAMAIITSAFFSSMSFAG 93
            ||  .||||||..|.:|..:....:.|...|..:.|.|......|.||.::.|:|...:.|...|
  Rat    11 YT--PPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGG 73

  Fly    94 LFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFNHY 158
            ..|..|..::|.|.|.:.||.|...|.....|..:...|.....|:.|......:....|....|
  Rat    74 PISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKY 138

  Fly   159 FVKNRVMWMSFAQTLIGLGSMLYPIVM----QKLMSWYGFRGCLLILTGLNAH-AVFGMLVMHPV 218
            |.|.|.:    |..|...||.::...:    |.....:|:||..|||.||..: .|.|.|
  Rat   139 FYKKRPL----ANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSL----- 194

  Fly   219 EWHMRRVPIQPEEQEELKELSPTVVIRVQPETPLKATREEPNFHTADPGARKLSHAEEQMLKVLS 283
               ||  ||.|::.:                                  ..||...|
  Rat   195 ---MR--PIGPQQGK----------------------------------VEKLKSKE-------- 212

  Fly   284 SRASSITSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIVDFLDL 348
                |:...|.       |||:..::             |.|     ....|.|..:|:..||||
  Rat   213 ----SLQEAGK-------SDANTDLI-------------GGS-----PKGEKLSVFQTVNKFLDL 248

  Fly   349 TLLKKPIFV-----NIVLGITFALYSDITFFTMQPVYLFELGYSRPDTATIIAIGAAADLASR-- 406
            :|.....|:     |:|:  .|.|::.:.|.:.   |.....:|...:|.:::|.|..|:.:|
  Rat   249 SLFTHRGFLLYLSGNVVM--FFGLFTPLVFLSN---YGKSKHFSSEKSAFLLSILAFVDMVARPS 308

  Fly   407 IFLAITAVCIQVPSRYIYLAGAVFTVFARFAFNGI--------TQFVGMACITAVIGFLRTWLHV 463
            :.||.....|:...:|.:.|..|        .||:        |.:||......|.||...||..
  Rat   309 MGLAANTRWIRPRVQYFFAASVV--------ANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSS 365

  Fly   464 PLPLVFADYLPKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHILNGFMILCAAPW 528
            .|.....|.:..:||::..||...::...:.|..|::|.:.|...||.:.:......:|:.....
  Rat   366 VLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYL 430

  Fly   529 VLEV-----LIVKFRRRNKIERNNVDHE---DVDNQGRSAM 561
            .:.:     |:.|.::..:.:|:..:.|   |||.:.:..|
  Rat   431 FIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTM 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS	40..>215	CDD:119392	47/179 (26%)
Slc16a1	NP_036848.1	2A0113	1..462	CDD:273325	124/550 (23%)
Slc16a1	NP_036848.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	446..494		6/26 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820