DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8028 and Slc16a5

DIOPT Version :9

Sequence 1:	NP_001097031.2	Gene:	CG8028 / 32923	FlyBaseID:	FBgn0031010	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001074403.1	Gene:	Slc16a5 / 217316	MGIID:	2443515	Length:	468	Species:	Mus musculus

Alignment Length:	504	Identity:	108/504 - (21%)
Similarity:	178/504 - (35%)	Gaps:	113/504 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LEAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKSIGAETSAMAIITSAFFSSMSFAGLF 95
            ||..||.|..:|.:...:.....|......|:.|.:..:...|..|..:...|...:.:...|..
Mouse     5 LEQADGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNSETSWFPSILGAMVHGGGPL 69

  Fly    96 SGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFNHYFV 160
            ...|.:.||.|...:.||:|..||..:..|:.|..||.:...|:.|........:..|....|||
Mouse    70 CSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLGMCFSFQSSITVVGLYFV 134

  Fly   161 KNRVMWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCLLILTGLNAH-AVFGMLVMHPVEWHMRR 224
            :.|.:..:.|...:.:|..|:|::.:.|:...|:||..||..|:..| .|.|.|:.
Mouse   135 RRRPLANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLR--------- 190

  Fly   225 VPIQPEEQEELKE---LSPTVVIRVQPETPLKATREEPNFHTADPGARKLSHAEEQMLKVLSSR- 285
             |:...|..|.||   |.|.:..|....|.:...|    :|.|              ..:|...
Mouse   191 -PVATNEVPEPKEDPLLPPKIPTRSCLATCVSTIR----YHLA--------------FDILRHNM 236

  Fly   286 -----ASSIT--SLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIV 343
                 .:.:|  :|| ::.|.:.  ..|..||                     |.....|...::
Mouse   237 GFCIYVTGVTWMNLG-FALPHIF--LVPYAMH---------------------HGVDDYWAAMLM 277

  Fly   344 DFLDLTLLKKPIFVNIVLGITFALYSDITFFTMQPVYLFELGYSRPDTATIIAIGAAADLASRIF 408
            ..:.        |.||.|                          ||....::| |..:..|.|.:
Mouse   278 SIVG--------FCNIFL--------------------------RPMAGLLLA-GRKSLAAYRKY 307

  Fly   409 LAITAVCIQVPSRYIYLAGAVFTVFARFAFNGITQFVGMACITAVIGFLRTWLHVPLPLVFADYL 473
            |...|:.|...:..|....|.|.|...:.   :...:.| |...::.|          .|..|.:
Mouse   308 LFAVAILINGLTNLICTVSADFRVLLGYC---LVYSLSM-CGVGILVF----------QVLMDIV 358

  Fly   474 PKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHILNGFMI 522
            |.:||.:..|||..:.|....:..|:.|.:.|||.::.:||::.:||::
Mouse   359 PMDRFPSALGLFTILCGVTSLISPPLAGLLLDKTNNFSYVFYMSSGFLV 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS	40..>215	CDD:119392	43/175 (25%)
Slc16a5	NP_001074403.1	2A0113	8..461	CDD:273325	106/501 (21%)
		MFS	32..413	CDD:119392	101/477 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	429..468
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010