Protein Alignment CG8028 and mct-4

DIOPT Version :10

• Sequence 1: NP_001097031.2
• Gene: CG8028 / 32923
• FlyBaseID: FBgn0031010
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001041267.1
• Gene: mct-4 / 180766
• WormBaseID: WBGene00003986
• Length: 777
• Species: Caenorhabditis elegans
• Alignment Length: 652
• Identity: 123/652 - (18%)
• Similarity: 223/652 - (34%)
• Gaps: 196/652 - (30%)

  Fly    32 EAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKSIG---AETSAMAI-ITSAFFSSMSFA 92
            :|||||:|.::...   .|.|.| .:......|.||.:|..   .|:..:.: |.|....:....
 Worm    68 QAPDGGYGWVIVFA---AFMSNL-VVDGISTAFSEFKQSYKERYQESDGLTVFIGSLIIGTYLLV 128

  Fly    93 GLFSGSLFQRFGMRQVGVTGGILYFLGTGMQLF---ATSTLHLIM-AFSVVQGFAFGLMVPTCYT 153
            |....:|..::..|.|.:.||::    :|:...   |:..:::.| .:.|:.|..||::......
 Worm   129 GPLVSALCNKYEQRYVVMAGGLI----SGIAFMIAPASPNIYVFMLIYGVMGGLGFGMIYLPAIV 189

  Fly   154 TFNHYFVKNRVMWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCLLILTGLNAHAVF-GMLV--- 214
            ....||...|.|....:....|:|:.|.|::.|..::..|::..:.:|..:....|| |.|.
 Worm   190 VVGFYFDSKRAMATGISVAGSGVGTFLVPLICQVCIANLGWQKTIWVLAVMIFSCVFYGYLYRPL 254

  Fly   215 ------------MHPVEWHMRRVPIQPEEQEELKELSPT-------------------VVIRVQ- 247
                        |.|:...:.:|  :.:|.|.::...|.                   .|.|::
 Worm   255 PMVDLNEIRDQEMEPLRQALSKV--EDDEDEAVESPHPNRSTSAASGAIEDEAVSQNPEVQRLRS 317

  Fly   248 --------PETPLK---------ATREEPNFHTADPGAR---KLSH---AEEQMLKVLSSR--AS 287
                    .|||..         |||...:..|::.|::   |||.   :.:..|..:|:|  ..
 Worm   318 ILTEGDEGSETPKSDAHKVRSHTATRSRKHTMTSNSGSQHDLKLSRGNLSSDNRLSRVSARDFNQ 382

  Fly   288 SITSLGNWSG----PVVVSDASPQ---------------MMHSLQTSRRPSTIAG--ASGAVAPA 331
            |::.|....|    .:.:|...|:               .:.:|:..:...|:||  ||....|.
 Worm   383 SLSKLSKSGGASNLSIAMSGVDPKEFQRPMNRQDIFYGGSIQNLKEFKEEGTMAGYRASTLSIPR 447

  Fly   332 HAT------------------------KKSWVRTIVD-----------------FLDLTLLKKP- 354
            ...                        ::..:...||                 .:||.|||..
 Worm   448 SVVGQAVSQLNLSRTGSRLGGPGIAEDEEEMIEPFVDDGCCKVLPLPMRNALSEMIDLNLLKNKT 512

  Fly   355 ---IFVNIVLGITFALYSDITFFTMQPVYLFELGYSRPDTATIIAIGAAADLASRIFLAITAVCI 416
               :.::.:||: ...|..|.|.                          .||:..:.|.::....
 Worm   513 MMILCISNLLGM-MGFYIPIMFL--------------------------KDLSESMKLDMSLAMF 550

  Fly   417 QVPSRYIY-LAGAVF-------TVFARFAFNGITQFVG----MAC--ITA---------VIGFLR 458
            .||...:: ..|.||       .:.:....|.::..|.    :||  :|:         |.||:.
 Worm   551 LVPIFGVFNTIGRVFFGWLTDQKILSALTINNLSLIVSGLLTLACPLLTSIAGQYFYAIVFGFII 615

  Fly   459 TWLHVPLPLVFADYLPKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHILNGFMIL 523
            :.......:|.||.:..|.....:||.:..:|.|..:..|..|.:.|.|..|...|: ..|.::|
 Worm   616 SAYICLTSIVLADLMGLENLTNSFGLLVVARGIASLVGPPFAGIVYDITGSYDTAFY-FGGLVLL 679

  Fly   524 CA 525
            .|
 Worm   680 VA 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8028	NP_001097031.2	MFS_MCT_SLC16	39..531	CDD:340910	118/645 (18%)
mct-4	NP_001041267.1	MFS_MCT_SLC16	75..>252	CDD:340910	39/184 (21%)
		MFS	<507..689	CDD:475125	41/203 (20%)