Protein Alignment Vav and She

DIOPT Version :9

• Sequence 1: NP_001097030.1
• Gene: Vav / 32920
• FlyBaseID: FBgn0040068
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: XP_001062249.1
• Gene: She / 685088
• RGDID: 1583215
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 376
• Identity: 80/376 - (21%)
• Similarity: 126/376 - (33%)
• Gaps: 126/376 - (33%)

  Fly   570 LDKL----VKETSPLHDDY------------RSLERAKE-----AMIDVSQYINEVKR--DSDHL 611
            |||.    .::|..:.:||            |..||..|     ...|..|.|.|::|  ..|.|
  Rat   197 LDKTKIMRQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPL 261

  Fly   612 VIIQKVKDSICD-------IHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLRYAFVFDKIL 669
            |...::.|..|:       ....:..:..|||  |:   ..:|:...:|..:..||.|
  Rat   262 VKALQLLDGPCEPGETMKVEATAKRRSSKDLL--GK---PPQLYDTPYEPSEGDLRAA------- 314

  Fly   670 IMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSE 734
             .|||   :..|.:....|....|:|  ||..                                |
  Rat   315 -EVKA---RPADGRLPEEDDRPAAEY--EQPW--------------------------------E 341

  Fly   735 HERDKWRKALTEAME-SLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISV 798
            .:|::..:||:...| |...||.:.....            :|..|.|
  Rat   342 WKREQIARALSVQFEGSDRSPGREEAGRP------------QHWQKTL----------------- 377

  Fly   799 HKGCISSTGRCKQNPVSVPPPVCDRQLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVRPQGPST 863
             |..:|..|    :...|.|.:.   |.:..|:.|::.|..|..||:..:...||:|....|.|
  Rat   378 -KPTLSDHG----DGEKVDPGLA---LEKQPWYHGSISRAEAESRLQPCKEAGYLVRNSESGNS- 433

  Fly   864 AHETMYALSLKTDDNVIKHMKINQENSGDSMLYCLSSRRHFKTIVELVSYY 914
                .|:::|||....: |:.:.|  :.||......:...|.:|.|:|.||
  Rat   434 ----KYSIALKTSQGCV-HIIVAQ--TKDSRYTLNQTSAVFDSIPEVVHYY 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vav	NP_001097030.1	CH	20..132	CDD:278723
		RhoGEF	428..603	CDD:279015	13/53 (25%)
		PH_Vav	624..753	CDD:269930	24/129 (19%)
		PH	641..749	CDD:278594	18/107 (17%)
		C1_1	761..804	CDD:278556	4/42 (10%)
		SH2_Vav_family	824..934	CDD:198193	26/91 (29%)
		SH3	940..993	CDD:302595
She	XP_001062249.1	SH2_SHE	399..496	CDD:198254	25/87 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910