| Sequence 1: | NP_001097030.1 | Gene: | Vav / 32920 | FlyBaseID: | FBgn0040068 | Length: | 1001 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_008870.2 | Gene: | SOS2 / 6655 | HGNCID: | 11188 | Length: | 1332 | Species: | Homo sapiens |
| Alignment Length: | 688 | Identity: | 131/688 - (19%) |
|---|---|---|---|
| Similarity: | 225/688 - (32%) | Gaps: | 247/688 - (35%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 132 LSQCRKVQ-QLHPDLIGFNLQLSPTERS--HSDEAIYKDLHSTDLNMRKTSSIDASASSSAEYYD 193
Fly 194 RTSQSGSLDENSDITIENGTEDIDDYIEDSLSNMCDSTIDNDAEDAGVETPLLSDCQGSHVRELS 258
Fly 259 FDLALDVVSSTTDGASNAVTPTPESYARQSQSPLAAAAPSVPVSAAPGPPMGRLVSTSSSSSSLL 323
Fly 324 VSE---SQRLQRAAAAVYNYRSSMASTEHEYAYIYSEDD-------EKVYEDLCYVTFQAKAKPE 378
Fly 379 VTTDNIACNGTGYDHTNTKEEEVYQDLCALHRTSRSQTASSTSFEQRDYVIRELIDTESNYLDVL 443
Fly 444 TALKTKFMGPLERHL-NQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAKVKMAQVFLDFREPF 507
Fly 508 LIYGEFCSLLLGAIDYLADVCKKN-----QIIDQLVQKCERDYNVGKLQLRD------------- 554
Fly 555 ----------ILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRD-- 607
Fly 608 ------------------SDHLVI-----IQKVKDSICDIHLLQNGNGSDLLQ-YGRLLLDGEL- 647
Fly 648 HIKA-HEDQKTKLRYAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTI----G 707
Fly 708 RDT-RFKYQLLLARKSGKTAFTLYLKSEHERDKWRKAL 744 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Vav | NP_001097030.1 | CH | 20..132 | CDD:278723 | 131/688 (19%) |
| RhoGEF | 428..603 | CDD:279015 | 36/203 (18%) | ||
| PH_Vav | 624..753 | CDD:269930 | 33/129 (26%) | ||
| PH | 641..749 | CDD:278594 | 30/111 (27%) | ||
| C1_1 | 761..804 | CDD:278556 | |||
| SH2_Vav_family | 824..934 | CDD:198193 | |||
| SH3 | 940..993 | CDD:302595 | |||
| SOS2 | NP_008870.2 | Histone | 63..169 | CDD:329110 | 24/194 (12%) |
| RhoGEF | 199..386 | CDD:238091 | 44/228 (19%) | ||
| PH_SOS | 437..543 | CDD:269963 | 31/116 (27%) | ||
| RasGEFN | 595..739 | CDD:214571 | |||
| RasGEF | 774..1013 | CDD:238087 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1018..1061 | ||||
| NupH_GANP | <1023..>1142 | CDD:318883 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1076..1096 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1142..1332 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||