Protein Alignment Vav and ARHGEF28

DIOPT Version :9

• Sequence 1: NP_001097030.1
• Gene: Vav / 32920
• FlyBaseID: FBgn0040068
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001073948.2
• Gene: ARHGEF28 / 64283
• HGNCID: 30322
• Length: 1731
• Species: Homo sapiens
• Identity: / - (0%)
• Similarity: / - (0%)
• Gaps: / - (0%)

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vav	NP_001097030.1	CH	20..132	CDD:278723
		RhoGEF	428..603	CDD:279015
		PH_Vav	624..753	CDD:269930
		PH	641..749	CDD:278594
		C1_1	761..804	CDD:278556
		SH2_Vav_family	824..934	CDD:198193
		SH3	940..993	CDD:302595
ARHGEF28	NP_001073948.2	ANK	<153..216	CDD:295348
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	473..524
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	630..649
		C1	653..698	CDD:237996
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	710..800
		RhoGEF	853..1042	CDD:214619
		PH_p190RhoGEF	1087..1187	CDD:275430
		PH	<1123..1188	CDD:278594
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1187..1207
		Interaction with PTK2/FAK1, required for regulation of axonal branching and synapse formation. /evidence=ECO:0000250	1295..1304
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1312..1339
		Mediates cytoplasmic retention and interaction with YWHAH. /evidence=ECO:0000250	1372..1383
		RNA-binding. /evidence=ECO:0000250	1496..1527
		Mediates cytoplasmic retention and interaction with MAPK8IP1. /evidence=ECO:0000250	1566..1579

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910