| Sequence 1: | NP_001097030.1 | Gene: | Vav / 32920 | FlyBaseID: | FBgn0040068 | Length: | 1001 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002882.3 | Gene: | RASGRF1 / 5923 | HGNCID: | 9875 | Length: | 1273 | Species: | Homo sapiens |
| Alignment Length: | 565 | Identity: | 124/565 - (21%) |
|---|---|---|---|
| Similarity: | 220/565 - (38%) | Gaps: | 139/565 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 333 AAAAVYNYRSSMASTEHE-----YAYIYS----------------EDDEKVYEDLCYVTFQAKAK 376
Fly 377 PEVT-----------TDNIACNGTGYDHTNTKEEEVYQD--LC------ALHRTSRSQTASSTSF 422
Fly 423 EQRDYVIRELIDTESNYLDVLTALKTKFMGPL-------ERHLNQDELRLIFPRIRELVDIHTKF 480
Fly 481 LDKLRESLTPNAKVKMAQVFLDFREPFL-IYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERD 544
Fly 545 YNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSD 609
Fly 610 HL---VIIQKVKDSICDIHL------LQNGNGSDLLQY----------GRLLLDGELHIKAHEDQ 655
Fly 656 KTKLRYAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYR-VEQSHS----RRTIGRD-TRFKY 714
Fly 715 QLLLARKSGKTAFTLYL--KSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHC 777
Fly 778 SKFLKGRIHQGYR--------------------------CKVCQI 796 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Vav | NP_001097030.1 | CH | 20..132 | CDD:278723 | |
| RhoGEF | 428..603 | CDD:279015 | 47/182 (26%) | ||
| PH_Vav | 624..753 | CDD:269930 | 33/152 (22%) | ||
| PH | 641..749 | CDD:278594 | 26/115 (23%) | ||
| C1_1 | 761..804 | CDD:278556 | 11/62 (18%) | ||
| SH2_Vav_family | 824..934 | CDD:198193 | |||
| SH3 | 940..993 | CDD:302595 | |||
| RASGRF1 | NP_002882.3 | PH | 489..583 | CDD:278594 | 21/96 (22%) |
| RasGEF_N | 647..>695 | CDD:279012 | 2/2 (100%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 724..754 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 809..874 | ||||
| REM | <938..1007 | CDD:295342 | |||
| RasGEF | 1034..1270 | CDD:214539 | |||
| PH_RasGRF1_2 | 19..154 | CDD:270081 | 10/33 (30%) | ||
| PH | 24..129 | CDD:278594 | 3/6 (50%) | ||
| RhoGEF | 244..425 | CDD:214619 | 47/182 (26%) | ||
| PH-like | 431..582 | CDD:302622 | 35/164 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||