Sequence 1: | NP_001097030.1 | Gene: | Vav / 32920 | FlyBaseID: | FBgn0040068 | Length: | 1001 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_065871.3 | Gene: | PREX1 / 57580 | HGNCID: | 32594 | Length: | 1659 | Species: | Homo sapiens |
Alignment Length: | 633 | Identity: | 152/633 - (24%) |
---|---|---|---|
Similarity: | 235/633 - (37%) | Gaps: | 187/633 - (29%) |
- Green bases have known domain annotations that are detailed below.
Fly 406 CALHRTSRSQTASSTSFEQRDYVIRELIDTESNYLDVLTALKTKFM--------GPLERHLNQDE 462
Fly 463 LRLIFPRIRELVDIHTKFLDKLRESL--TPNAKVKMAQVFLDFREPFLIYGEFCSLLLGAIDYLA 525
Fly 526 DVCKKNQIIDQLVQKCERDYNVGKLQLRDI-----LSVPMQRILKYHLLLDKLVKETSPLHDDYR 585
Fly 586 SLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQY-GRLLLDGE-LH 648
Fly 649 IKAHEDQKTKLRYAFVFDKILIMVKALHIKTGDMQ------------YTYRDSHN---------- 691
Fly 692 --LADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTA----FTLYLKSEHERDKWRKAL---TEA 747
Fly 748 MESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGR--IHQGYRCKVCQISVHKGCISSTGRCK 810
Fly 811 QNPVSVPPPVCDRQLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVRPQGPSTAHETMYALSLKT 875
Fly 876 DDNVIKHMKINQENSGDSMLYCLSSRRHFKTIVELVSYYERNDLGENFA----------GLN--- 927
Fly 928 --QSLQWP-----------YKEVI-ATALYDYEPKAGSNQLQLRTDCQ 961 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Vav | NP_001097030.1 | CH | 20..132 | CDD:278723 | |
RhoGEF | 428..603 | CDD:279015 | 54/189 (29%) | ||
PH_Vav | 624..753 | CDD:269930 | 41/161 (25%) | ||
PH | 641..749 | CDD:278594 | 35/139 (25%) | ||
C1_1 | 761..804 | CDD:278556 | 8/44 (18%) | ||
SH2_Vav_family | 824..934 | CDD:198193 | 26/135 (19%) | ||
SH3 | 940..993 | CDD:302595 | 6/22 (27%) | ||
PREX1 | NP_065871.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..40 | 2/2 (100%) | |
RhoGEF | 50..238 | CDD:238091 | 54/191 (28%) | ||
PH_Collybistin_ASEF | 244..396 | CDD:269931 | 40/174 (23%) | ||
DEP | 414..494 | CDD:321936 | 24/132 (18%) | ||
DEP_2_P-Rex | 506..598 | CDD:239887 | 13/62 (21%) | ||
PDZ_signaling | 627..703 | CDD:238492 | |||
PDZ | 721..773 | CDD:238080 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 796..819 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1291 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.940 |