DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vav and AgaP_AGAP010472

DIOPT Version :9

Sequence 1:	NP_001097030.1	Gene:	Vav / 32920	FlyBaseID:	FBgn0040068	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	XP_001689404.1	Gene:	AgaP_AGAP010472 / 5668042	VectorBaseID:	AGAP010472	Length:	248	Species:	Anopheles gambiae

Alignment Length:	241	Identity:	57/241 - (23%)
Similarity:	90/241 - (37%)	Gaps:	63/241 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 AIYKDLHSTDLNMRKTSSIDASASSSAEYYDRTSQSGSLDENSDITIENGTEDIDDYIEDSLSNM 227
            |::....:|.:...:|:|.|.|:||||              .:..|:...|..:..|   .|||.
Mosquito     8 AVHTATTATTITTARTTSADISSSSSA--------------TAIATVSTNTTCLTGY---QLSNT 55

  Fly   228 CDSTIDNDAEDAGVET-------PLLSDCQGSHVRELSFDLALDVVSSTTDGASNAV----TPTP 281
            .:|...:.:..|...|       |:..:.|             .|.|.::..|..||    |...
Mosquito    56 TNSPTSSSSPPATSPTDRSITSAPITGNPQ-------------SVTSGSSSSAITAVVSSGTKRT 107

  Fly   282 ESYARQSQSPL---AAAAPSVPVSAAPGPP-------MGRLVSTSSSSSSLLVSESQRLQRAAAA 336
            .|...:|.|||   ..::||..||:..|||       :..:.|.|.:::....|....:...:..
Mosquito   108 RSLLLKSTSPLQQTTHSSPSHTVSSPQGPPVPPRLSHIHAIGSVSPANTGPTFSNHPSIDPISTT 172

  Fly   337 VYNYRSSMASTEHEYAYIYSEDDEKVYEDLCYVTFQAKAKPEVTTD 382
            .    ||.||:|   |.:.|    .:....||||....| |.:|:|
Mosquito   173 T----SSNASSE---AIVMS----SIVTGTCYVTPPTPA-PLITSD 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Vav	NP_001097030.1	CH	20..132	CDD:278723
		RhoGEF	428..603	CDD:279015
		PH_Vav	624..753	CDD:269930
		PH	641..749	CDD:278594
		C1_1	761..804	CDD:278556
		SH2_Vav_family	824..934	CDD:198193
		SH3	940..993	CDD:302595
AgaP_AGAP010472	XP_001689404.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910