| Sequence 1: | NP_001097030.1 | Gene: | Vav / 32920 | FlyBaseID: | FBgn0040068 | Length: | 1001 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_062645.2 | Gene: | Net1 / 56349 | MGIID: | 1927138 | Length: | 595 | Species: | Mus musculus |
| Alignment Length: | 571 | Identity: | 120/571 - (21%) |
|---|---|---|---|
| Similarity: | 203/571 - (35%) | Gaps: | 146/571 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 206 DITIENGTEDIDDYIEDSLSNMCDSTIDNDAEDAGVETPLLSDCQGSHVRELSFDLAL-DVVSST 269
Fly 270 TDGASNAVTPTPESYARQS--QSPLAAAAPSVPVSAAPGPPMGRLVSTSSSSSSLLVSESQRLQR 332
Fly 333 AAAAVYNYRSSMASTE---HEYAYIYSEDDEKVYEDLCYVTFQAKAKPEVTTDNIACNGTGYDHT 394
Fly 395 NTKEEEVYQDLCALHRTSRSQTASSTSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLN 459
Fly 460 QDELRLIFPRIRELVDIHTKFLDKLRESLTPNAKV-KMAQVFLDFREPFLIYGEFCSLLLGAIDY 523
Fly 524 LADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLE 588
Fly 589 RAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLL-DGELHIKAH 652
Fly 653 EDQKTKLRYAFVFDKILIMVKALHIKTGDMQYTYRDS--------HNLADYRVEQSHS-RRTIGR 708
Fly 709 DTRFK--YQLLLARKSGKTAFTLYLKSEHERDKW----RKALTEAMESLEP 753 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Vav | NP_001097030.1 | CH | 20..132 | CDD:278723 | |
| RhoGEF | 428..603 | CDD:279015 | 41/175 (23%) | ||
| PH_Vav | 624..753 | CDD:269930 | 29/144 (20%) | ||
| PH | 641..749 | CDD:278594 | 28/123 (23%) | ||
| C1_1 | 761..804 | CDD:278556 | |||
| SH2_Vav_family | 824..934 | CDD:198193 | |||
| SH3 | 940..993 | CDD:302595 | |||
| Net1 | NP_062645.2 | Necessary for nuclear localization | 1..74 | 2/11 (18%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..42 | ||||
| Nuclear localization signal | 12..19 | ||||
| Nuclear localization signal | 66..72 | 0/5 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 127..151 | 8/24 (33%) | |||
| RhoGEF | 178..354 | CDD:214619 | 48/251 (19%) | ||
| PH_Net1 | 368..502 | CDD:270044 | 30/145 (21%) | ||
| PH | 387..501 | CDD:278594 | 28/118 (24%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 555..595 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||