DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vav and she

DIOPT Version :9

Sequence 1:	NP_001097030.1	Gene:	Vav / 32920	FlyBaseID:	FBgn0040068	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	XP_689987.3	Gene:	she / 561493	ZFINID:	ZDB-GENE-090915-6	Length:	438	Species:	Danio rerio

Alignment Length:	151	Identity:	38/151 - (25%)
Similarity:	66/151 - (43%)	Gaps:	29/151 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   799 HKGCISSTGRCKQNP--------VSVPP----PVCD--RQLSEFNWFAGNMDRETAAHRLENRRI 849
            ||..  :|...:.||        .|:.|    |:.|  ..|.:.:|:.|::.|:.|..:|:..|.
Zfish   296 HKSW--TTKSLRPNPPSPTSPSSPSITPDSETPIVDPTLPLEKQSWYHGSVSRQEAEAQLQQCRE 358

  Fly   850 GTYLLRVRPQGPSTAHETMYALSLKTDDNVIKHMKINQENSGDSMLYCL-SSRRHFKTIVELVSY 913
            .::|:|     .|.:..:.|:::|||....:..:....:..|    |.| .|...|.:|.|:|.:
Zfish   359 ASFLVR-----DSESATSKYSIALKTSQGCVHIIVAQTKECG----YTLEKSSCVFPSIPEVVHH 414

  Fly   914 YERNDLGENFAGL-NQSLQWP 933
            |....|  .|.|. :.:||.|
Zfish   415 YCTQRL--PFTGAEHMTLQHP 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vav	NP_001097030.1	CH	20..132	CDD:278723
		RhoGEF	428..603	CDD:279015
		PH_Vav	624..753	CDD:269930
		PH	641..749	CDD:278594
		C1_1	761..804	CDD:278556	2/4 (50%)
		SH2_Vav_family	824..934	CDD:198193	29/112 (26%)
		SH3	940..993	CDD:302595
she	XP_689987.3	SH2_SHE	337..434	CDD:198254	28/108 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910