DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vav and arhgef9b

DIOPT Version :9

Sequence 1:NP_001097030.1 Gene:Vav / 32920 FlyBaseID:FBgn0040068 Length:1001 Species:Drosophila melanogaster
Sequence 2:XP_021336708.1 Gene:arhgef9b / 560923 ZFINID:ZDB-GENE-030131-7745 Length:573 Species:Danio rerio


Alignment Length:302 Identity:64/302 - (21%)
Similarity:106/302 - (35%) Gaps:97/302 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   160 SDEAIY-KDLHSTDLNMRKTSSIDASASSSAEYYD-----RTSQSGS-LDENSDITIE-NGTEDI 216
            |:..|| |..|....|...:|.|:...|.:.:.:.     |.|:.|. |:....|::: .|::.:
Zfish   205 SERVIYTKKSHPNFSNCNNSSVIEPEDSCAKQSFKIPQRRRWSRGGDVLNYLRRISLKGKGSQTL 269

  Fly   217 DDYIEDSLSNMCDSTIDNDAEDAGVETPLLSDCQGSHVRELSFDLALDVVS----STTDGAS--- 274
            .:...:|: |..|.|||:|              .||    :||:|..|:.|    |..||.|   
Zfish   270 AESSFESM-NTLDKTIDSD--------------YGS----VSFELVKDLNSAPEQSGVDGKSGHF 315

  Fly   275 -------NAVTPTPESYARQSQSPLAAAAPSVPVSAAPGPPMGRLVSTSSSSSSLLVSESQRLQR 332
                   |.|..|...:...|:|              ..||.|:       .|.|   :.::.|:
Zfish   316 RGLLRFFNTVAETAMKWRNSSRS--------------FSPPEGQ-------QSQL---DLRKTQQ 356

  Fly   333 AAAAVYNYRSSMASTEHEYAYIYSEDDEKVYE------DLCYVTFQAKAK--------------- 376
            :...:.|....:.| ||       :||..|:.      |:|.|......|               
Zfish   357 SGELIQNTPLPVRS-EH-------KDDTSVHGKSTLPLDMCKVVSTVNDKVDCSPPVVLKAWRTC 413

  Fly   377 PEVTTD-NIACNGTGYDHTNTKEEEVYQDLCALHRTSRSQTA 417
            |:...| |..||.:  |.:.::....:..|..:....|.:.|
Zfish   414 PDSPRDSNSLCNNS--DESQSQISSTHISLATIESHPRYEEA 453

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
VavNP_001097030.1 CH 20..132 CDD:278723
RhoGEF 428..603 CDD:279015
PH_Vav 624..753 CDD:269930
PH 641..749 CDD:278594
C1_1 761..804 CDD:278556
SH2_Vav_family 824..934 CDD:198193
SH3 940..993 CDD:302595
arhgef9bXP_021336708.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1291
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.940

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