| Sequence 1: | NP_001097030.1 | Gene: | Vav / 32920 | FlyBaseID: | FBgn0040068 | Length: | 1001 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011535239.1 | Gene: | ARHGEF40 / 55701 | HGNCID: | 25516 | Length: | 1523 | Species: | Homo sapiens |
| Alignment Length: | 744 | Identity: | 155/744 - (20%) |
|---|---|---|---|
| Similarity: | 267/744 - (35%) | Gaps: | 235/744 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 113 PTMLYD-----------LTNFHRVLITLSKLSQC-RKVQQLHPDLIGFNLQLSPTERSHSDEAIY 165
Fly 166 KD----LHSTDLNMRKTSSIDASASSSAEYYDRTSQSG---SLDENS------DI------TIEN 211
Fly 212 GT----------EDIDDYIEDSLSNMCDSTIDNDAEDAGV---ETPLLSDCQGSHVRELSFDLAL 263
Fly 264 DVVSSTTDGASNAV-----------------------TPTPESYARQSQSPLAAAAPSVPVSAAP 305
Fly 306 GPPMGRLVSTSSSSSSLLVSESQRLQRAAAAVYNYRSSMASTEHEYAYIYSEDDEKVYEDLCYVT 370
Fly 371 FQAKAKP---------EVTTDNIACNGTGYDHTNTKEEEVYQDLCALHR---------TSRSQTA 417
Fly 418 SSTSFEQRDYVIRELIDTESNYLDVLT--------ALKTKFMGPLERHLNQDELRLIFPRIRELV 474
Fly 475 DIHTKFLDKLRESLTPNAKVKMAQVFLDFREPFLIYGEFCS---LLLGAIDYLADVCKKNQIIDQ 536
Fly 537 LVQKCERDYNVGKLQ----LRDILSVPMQRILKYHLLLDKLVKETSP-LHDDYRSLERAKEAMID 596
Fly 597 VSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHED------- 654
Fly 655 QKTKLRYAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLA 719
Fly 720 RKSGKTAFTLYLKSEHERDKWRKALTEAM 748 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Vav | NP_001097030.1 | CH | 20..132 | CDD:278723 | 6/29 (21%) |
| RhoGEF | 428..603 | CDD:279015 | 39/190 (21%) | ||
| PH_Vav | 624..753 | CDD:269930 | 30/132 (23%) | ||
| PH | 641..749 | CDD:278594 | 26/115 (23%) | ||
| C1_1 | 761..804 | CDD:278556 | |||
| SH2_Vav_family | 824..934 | CDD:198193 | |||
| SH3 | 940..993 | CDD:302595 | |||
| ARHGEF40 | XP_011535239.1 | SPEC | 786..964 | CDD:295325 | 36/202 (18%) |
| RhoGEF | 1086..1245 | CDD:295373 | 41/195 (21%) | ||
| PH_puratrophin-1 | 1244..1379 | CDD:270062 | 34/154 (22%) | ||
| PH | 1269..1367 | CDD:278594 | 27/112 (24%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||