| Sequence 1: | NP_001097030.1 | Gene: | Vav / 32920 | FlyBaseID: | FBgn0040068 | Length: | 1001 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_005260495.1 | Gene: | PLCG1 / 5335 | HGNCID: | 9065 | Length: | 1330 | Species: | Homo sapiens |
| Alignment Length: | 807 | Identity: | 158/807 - (19%) |
|---|---|---|---|
| Similarity: | 268/807 - (33%) | Gaps: | 292/807 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 396 TKEEEVYQDLCALHRTSRSQTASSTSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQ 460
Fly 461 DELRLIFPRIRELVDIHTKFLDKLRESLTPNAKVKMAQVFLDFREPFLIYGEFC----SLLLGA- 520
Fly 521 ----IDYL----------ADVCKKNQIIDQLVQKCERDYN-----VGKLQLRD----ILSVPMQR 562
Fly 563 ILKYHLLLDKLV-----KETS----------------PL--------HDDYR-----SLERAKEA 593
Fly 594 ----------------------------------MIDVSQYINEVKRD----SDHLVIIQKVKDS 620
Fly 621 ICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHE------DQKTKLRYAFVFDKILIMVKAL---- 675
Fly 676 ---HIKTGDMQYTYRDSHN--------LADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTL 729
Fly 730 YLKSE----------------------HERDKW---------------RKALTE-AMESLEPPG- 755
Fly 756 --CQSTDHKMEIYT--FDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGCISST---------- 806
Fly 807 --GRCKQNPVSVPPPVCDRQLSEF-NWFAGNMDRETAAHRLEN-RRIGTYLLRVRPQGPSTAHET 867
Fly 868 MYALSLKTDDNVIKHMKINQENSGDSMLYCLSSRRHFKTIVELVSYYERN--------------- 917
Fly 918 ----------DLGENFAGLN-----QSLQWPYKEVIATALYDYEPKAGSNQLQLRTDCQVLVIGK 967
Fly 968 DGDSKGWWRGKIGDTVG-YFPKEYVQE 993 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Vav | NP_001097030.1 | CH | 20..132 | CDD:278723 | |
| RhoGEF | 428..603 | CDD:279015 | 50/270 (19%) | ||
| PH_Vav | 624..753 | CDD:269930 | 34/187 (18%) | ||
| PH | 641..749 | CDD:278594 | 29/166 (17%) | ||
| C1_1 | 761..804 | CDD:278556 | 8/44 (18%) | ||
| SH2_Vav_family | 824..934 | CDD:198193 | 32/141 (23%) | ||
| SH3 | 940..993 | CDD:302595 | 14/53 (26%) | ||
| PLCG1 | XP_005260495.1 | PH_PLC_gamma | 29..151 | CDD:270168 | 6/25 (24%) |
| PH | <71..142 | CDD:278594 | 5/16 (31%) | ||
| PI-PLCc_gamma | 319..>466 | CDD:176534 | 30/158 (19%) | ||
| PH-like | 489..>523 | CDD:302622 | 6/50 (12%) | ||
| SH2_N-SH2_PLC_gamma_like | 545..649 | CDD:199829 | 19/109 (17%) | ||
| SH2_C-SH2_PLC_gamma_like | 663..765 | CDD:198186 | 28/113 (25%) | ||
| SH3_PLCgamma1 | 791..850 | CDD:212903 | 15/61 (25%) | ||
| PHsplit_PLC_gamma | <864..933 | CDD:270054 | |||
| PLCYc | 954..1069 | CDD:128454 | |||
| C2_PLC_like | 1087..1250 | CDD:175974 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||