DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vav and CG15611

DIOPT Version :9

Sequence 1:NP_001097030.1 Gene:Vav / 32920 FlyBaseID:FBgn0040068 Length:1001 Species:Drosophila melanogaster
Sequence 2:NP_611189.2 Gene:CG15611 / 36930 FlyBaseID:FBgn0034194 Length:508 Species:Drosophila melanogaster


Alignment Length:527 Identity:104/527 - (19%)
Similarity:199/527 - (37%) Gaps:151/527 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   262 ALDVVSSTTDGASNAVTPTPESYARQSQSPLAAAAPSVPVSAAPGPPMGRL------------VS 314
            ::|||..         .|..|....:||||.:..|.::|.|.|..  .|:|            :|
  Fly    45 SIDVVDK---------APAKECPLLESQSPSSPIATTLPKSQASS--NGKLEKQISLLDSDSGIS 98

  Fly   315 TSS-SSSSLLVSESQRLQRAAAAVYNYRSSMASTE---HEYAYIYSEDDEKVYEDLCYVTFQAKA 375
            .|| ::.|...:.|....||....:::.|...|.|   .||   :.::|....|:|         
  Fly    99 LSSINTCSTTAANSSPTYRAPNGFHSFPSHTLSFETLGDEY---HEDEDTLSLENL--------- 151

  Fly   376 KPEVTTDNIACNGTGYDHTNTKEEEVYQDLCALHRTSRSQTASSTSFEQRDYVIRELIDTESNYL 440
                    ..|:.|          |:|                  :.::..::|.|||.||.||:
  Fly   152 --------FPCDQT----------EIY------------------ASKKISFIIDELIQTEVNYV 180

  Fly   441 D-----VLTALKTKFMGPLERHLN-QDELRLIFPRIRELVDIHTKFLDKLRESLTPNAKVKMAQV 499
            :     :|...:.|.:..|...|: :.:.:::...|:|::::|.|   ::...:..|.: .:..:
  Fly   181 NNLKKGMLNYGQLKDVEDLPEALSGETKQKMLLGNIKEILELHEK---EILPLMLRNQR-DLKGL 241

  Fly   500 FLDFREPFLIYGEFC--SLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSV---- 558
            |.:|...|.....:|  |..:|         ||:.:  ||.|.........:.|::|.|.:    
  Fly   242 FDEFAAHFEKNSFYCYVSFTMG---------KKSSM--QLRQDNRLWLQTYQTQIKDKLGIDSFL 295

  Fly   559 --PMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSI 621
              |:||:.:|.|||.:.:.|.      |:|....|..:..|.:....::|..|   ::.:.:   
  Fly   296 VQPIQRLTRYPLLLQQFISEF------YKSGISCKPVLTAVCKLETRMRRALD---VVNQAE--- 348

  Fly   622 CDIHLLQNGNGSDLLQYGRLLLDGEL---HIKAHEDQKTKLRYAFVFDKILIMVKALHIKTGDMQ 683
             :|..::..|..|:||.|......|.   |....:..::|:   |:||:.|:..     :....:
  Fly   349 -EIPNIEELNELDVLQLGNFRRATEFDAQHFPTRKKYRSKV---FLFDRCLVCT-----EVRKKR 404

  Fly   684 YTYRDSHN-------------------LADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTL 729
            ..||..:|                   :.:..|:|.....::| ..|.:|..:.|..|   ....
  Fly   405 LAYRQHYNWEHVELQRPLDSVSSNANKIINLLVKQEEGGSSVG-SKREEYSFMAAEAS---VVKQ 465

  Fly   730 YLKSEHE 736
            :|::.|:
  Fly   466 WLQATHK 472

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
VavNP_001097030.1 CH 20..132 CDD:278723
RhoGEF 428..603 CDD:279015 43/188 (23%)
PH_Vav 624..753 CDD:269930 25/135 (19%)
PH 641..749 CDD:278594 19/118 (16%)
C1_1 761..804 CDD:278556
SH2_Vav_family 824..934 CDD:198193
SH3 940..993 CDD:302595
CG15611NP_611189.2 RhoGEF 167..313 CDD:238091 38/160 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45462282
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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