Protein Alignment Vav and CG30456

DIOPT Version :9

• Sequence 1: NP_001097030.1
• Gene: Vav / 32920
• FlyBaseID: FBgn0040068
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_611188.3
• Gene: CG30456 / 36929
• FlyBaseID: FBgn0050456
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 709
• Identity: 143/709 - (20%)
• Similarity: 234/709 - (33%)
• Gaps: 233/709 - (32%)

  Fly   151 QLSPTERSHSDEAIYKDLHSTDLNMRKTSSIDASASSSAEYYDRTSQSGSLDENSDITIENGTED 215
            |.:..|| ||...:..:|.|.|: .|..||:.:|:||....|...|.:.|...:..:...:..|.
  Fly    34 QAAEQER-HSSTLVSSNLESNDV-ARPVSSVSSSSSSIQLSYSVNSDTDSSYRHRSLLKMHEAES 96

  Fly   216 IDDYIEDSL--SNMCDSTIDNDAEDAGVETPLLSDCQGSHVRELSFDLALDVVSSTTDG---ASN 275
            :.....:|.  |.|...|.|          |.|.|.:....|..:|...:..:......   ..|
  Fly    97 VGGLGTESTPESPMSPQTPD----------PALLDVRQKVHRFEAFRTNICFIKQERHSLKLLEN 151

  Fly   276 AVTPTPESYARQSQSPLAAAAPSVPVSAAPGPPMGRLVSTSSSSSSLLVS-----ESQRLQRAAA 335
            ...|:.|..:....:|     |:.|......|.:|   |..||.||.:.|     ...|.:....
  Fly   152 RRHPSFEDQSEDHHTP-----PATPPRRIRLPGLG---SRGSSRSSSIPSFQAGIHEVRSEDEVD 208

  Fly   336 AVYNYRSSMASTEHEY-------AYIYSED--DEKVYEDLCYVTFQA------------------ 373
            .:.::.:...:...||       ..:.||:  |.||.:.....:..|
  Fly   209 QISDFETDSHTAAEEYLVVDTTSEVVPSEEVADSKVDQQQVQRSISADQSKEALTLPLKMRNDFP 273

  Fly   374 ---KAKPEVTTDNIACNGTGYDHTNTKEEEVYQDLCALHRTSRSQTASSTSFEQRDY-------V 428
               ::.|...|:.|   ||..:|...|...|||.         .........|.||.       :
  Fly   274 RNYRSTPRRKTEII---GTTNEHLVGKFHSVYQP---------KDEEEEVEIELRDKSDKCVHPI 326

  Fly   429 IRELIDTESNYLDVLTALKTKFMGPLERHLN---QDELRL--------IFPRIRELVDIH-TKFL 481
            :.|||.||..|::.|      |.| :|.:.|   :.:|.|        :|..|.::.:.| .:||
  Fly   327 LEELIKTEEAYVNNL------FTG-IENYGNIFQRKDLPLGLRGKKYDLFGNIEQIAEFHRDEFL 384

  Fly   482 DKL---RESLTPNAKVKMAQVFLDFREPFLIYG------------EFCSLLLGAIDYLADVCKKN 531
            ..|   |..|.     ::...||.|.:....||            :.|.|..   :|...:
  Fly   385 PMLQRNRRDLK-----RLFDEFLQFLDQHCFYGYVIFTMNKQKSLKLCDLYK---NYFTSI---- 437

  Fly   532 QIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMID 596
                    :.|||   .||.:...|..|:||:.:|.|||
  Fly   438 --------RLERD---DKLGINSFLVQPIQRMARYPLLL-------------------------- 465

  Fly   597 VSQYINEVKRDSDHLVIIQKVKDSICDIH-----LLQNGNGSDLLQ------------YGRLLLD 644
             :|:||...::.|  ::::.:.:|.|.:.     ||...|.|:::.            .|:....
  Fly   466 -TQFINTFFKNRD--IVMKPLIESCCRLEKRLRALLTTTNESEIINDIVDCHEFNVYYQGKFRKV 527

  Fly   645 GELHIKAHEDQKTKLRYAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSR---RTI 706
            .|..:..|:.:::.....|:|||.:|             ||.....||.      .|.|   ..|
  Fly   528 NEFQVLDHKLKRSYRSKVFIFDKCII-------------YTEIKGKNLL------FHGRYPCEHI 573

  Fly   707 GRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEI 765
            |...:.|            :||||    :||.|.::             |:.|...::|
  Fly   574 GISAKTK------------SFTLY----YERRKQQE-------------CEFTADPVQI 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vav	NP_001097030.1	CH	20..132	CDD:278723
		RhoGEF	428..603	CDD:279015	44/201 (22%)
		PH_Vav	624..753	CDD:269930	28/148 (19%)
		PH	641..749	CDD:278594	23/110 (21%)
		C1_1	761..804	CDD:278556	1/5 (20%)
		SH2_Vav_family	824..934	CDD:198193
		SH3	940..993	CDD:302595
CG30456	NP_611188.3	RhoGEF	326..470	CDD:279015	43/200 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930