DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vav and Stac2

DIOPT Version :9

Sequence 1:NP_001097030.1 Gene:Vav / 32920 FlyBaseID:FBgn0040068 Length:1001 Species:Drosophila melanogaster
Sequence 2:XP_038942431.1 Gene:Stac2 / 363674 RGDID:1305548 Length:439 Species:Rattus norvegicus


Alignment Length:365 Identity:85/365 - (23%)
Similarity:137/365 - (37%) Gaps:105/365 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   711 RFKYQLLLAR-KSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPG--CQSTD------------ 760
            |||..|.|.. ...|:....:|:|..|.....:.|......|.||.  ..|||            
  Rat    33 RFKRSLSLKTILRSKSVENFFLRSGSELKCPTEVLLTPPTPLPPPSPPPASTDRGLPTPTPSPCP 97

  Fly   761 -------------HKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGC---------- 802
                         |..:.:.|...:.|..|.:.:.|...||.|||.|::|||..|          
  Rat    98 VPRPLAPLKPVRLHSFQEHVFKRASPCELCHQLIVGNSKQGLRCKTCKVSVHLWCSEEISHQQCP 162

  Fly   803 ---ISSTGRCKQNPVSV--PPPVCDRQLSEFNWFAGNMDRETAAHRLENRRIGTYL-LRVRPQGP 861
               .:|..|...:|:.|  |||.|  .:|:.:...|...:....:  |..|.||.| |..|....
  Rat   163 GKTSTSFRRNFSSPLLVHEPPPAC--AMSKESPPTGTSGKVDPVY--ETLRYGTSLALMNRSSFS 223

  Fly   862 STAHETMYALSLK---TDDNVIKHMKINQENSGDSML---------------------------- 895
            ||:.....:||.:   |:|.. ..::.::|..|||:.                            
  Rat   224 STSESPTRSLSERDELTEDGE-GSIRSSEEGPGDSVFTAPVESEGSGAEEKSPGQQTPGASMHIH 287

  Fly   896 --YCLSSRRHFKTIVELVSYYE------RNDLGENFAGLNQSLQWPYKEVIATALYDYEPKAGSN 952
              :.:...|::.||.:...:.:      |.|:|..::              ..|||.:.|:. :|
  Rat   288 SKWTMGGARNWPTITDPELFLQPPKLPVRKDVGPMYS--------------YVALYKFLPQE-NN 337

  Fly   953 QLQLRTDCQVLVIGKDGDSKGWWRGKIGDTVGYFPKEYVQ 992
            .|.|:...:::::  |..::.||:|||||.||:||..:||
  Rat   338 DLALQPGDRIMLV--DDSNEDWWKGKIGDRVGFFPANFVQ 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
VavNP_001097030.1 CH 20..132 CDD:278723
RhoGEF 428..603 CDD:279015
PH_Vav 624..753 CDD:269930 11/42 (26%)
PH 641..749 CDD:278594 10/38 (26%)
C1_1 761..804 CDD:278556 15/55 (27%)
SH2_Vav_family 824..934 CDD:198193 25/149 (17%)
SH3 940..993 CDD:302595 21/53 (40%)
Stac2XP_038942431.1 C1_Stac2 106..164 CDD:410431 15/57 (26%)
STAC2_u1 167..323 CDD:406951 33/160 (21%)
SH3_Stac2_C 324..376 CDD:212918 21/69 (30%)
SH3 383..434 CDD:418401
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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