DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vav and Lrch4

DIOPT Version :9

Sequence 1:	NP_001097030.1	Gene:	Vav / 32920	FlyBaseID:	FBgn0040068	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	XP_038945505.1	Gene:	Lrch4 / 360779	RGDID:	1306145	Length:	695	Species:	Rattus norvegicus

Alignment Length:	73	Identity:	24/73 - (32%)
Similarity:	36/73 - (49%)	Gaps:	11/73 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LAMTLRDGVLLCNLVIHLDPSSL------DPREFNRKPQMAQFLCSKNIKLFLDVCHNNFGIRDA 108
            ||..|.:||:||.|...|.|.|:      .|    ..|:::.....||::.||:.| ...|:.:|
  Rat   572 LAEALANGVILCQLANQLRPRSVPFIHVPSP----AVPKLSALKSRKNVENFLEAC-RKMGVPEA 631

  Fly   109 DLFEPTML 116
            ||..|:.|
  Rat   632 DLCSPSDL 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vav	NP_001097030.1	CH	20..132	CDD:278723	24/73 (33%)
		RhoGEF	428..603	CDD:279015
		PH_Vav	624..753	CDD:269930
		PH	641..749	CDD:278594
		C1_1	761..804	CDD:278556
		SH2_Vav_family	824..934	CDD:198193
		SH3	940..993	CDD:302595
Lrch4	XP_038945505.1	LRR	25..264	CDD:227223
		leucine-rich repeat	46..72	CDD:275380
		leucine-rich repeat	79..101	CDD:275380
		leucine-rich repeat	102..124	CDD:275380
		leucine-rich repeat	125..144	CDD:275380
		leucine-rich repeat	147..169	CDD:275380
		leucine-rich repeat	170..192	CDD:275380
		leucine-rich repeat	193..213	CDD:275380
		leucine-rich repeat	215..237	CDD:275380
		PHA03247	<280..507	CDD:223021
		CH_LRCH4	548..654	CDD:409122	24/73 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910