Protein Alignment Vav and CG43658

DIOPT Version :9

• Sequence 1: NP_001097030.1
• Gene: Vav / 32920
• FlyBaseID: FBgn0040068
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001259643.1
• Gene: CG43658 / 32729
• FlyBaseID: FBgn0263706
• Length: 2263
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 123/633 - (19%)
• Similarity: 221/633 - (34%)
• Gaps: 149/633 - (23%)

  Fly   179 SSIDASASSSAEYYDRT---SQSGSLDENSDITIENGTEDIDDYIEDSLSNMCDSTIDNDAEDAG 240
            ||.:....|.....||.   .:....|:|.|:    |.|::....|.:.|::...:..|.....
  Fly   701 SSSERDTKSPCRERDRNLERDRDRERDKNDDL----GEEEVLTEEEQTSSSVSSLSAGNQRNSQ- 760

  Fly   241 VETPLLSDCQGSHVRELSFDLALDVVSSTTDGASNAVTPTPESYARQSQSPLA------AAAPSV 299
                 |........:.||||......:.:..|:::.    |.|.|..|.:..:      |:|.::
  Fly   761 -----LRSTFNKAKQHLSFDKWRTAATGSATGSASG----PGSSATDSNNAASNMIMRRASACTM 816

  Fly   300 PVSAAPGPPMGRLVSTSSSSSSLLVSESQ--RLQRAAAAVYNYRSSMASTEHEYAYIYSEDDEKV 362
            |.|...|   |..|.:|....:....||.  ||.|       :.|....:.|:|. :...|..
  Fly   817 PSSGGGG---GAGVGSSQREEATTPGESPGGRLSR-------WFSIRRGSSHQYD-VGGRDGR-- 868

  Fly   363 YEDLCYVTFQAKAKPEVTTDNIACN------GTG--------YDHTNTKE-------------EE 400
                 :.|..:...|:..:.|...|      |||        .|..:.::             .|
  Fly   869 -----HSTASSFDTPDSGSGNSPKNGSNAVAGTGGAGSQGVALDAASPQKLANLGASKMMPGVPE 928

  Fly   401 VYQDLCALHR---------TSRSQTASSTSFE-------------------QRDYVIRELIDTES 437
            ...|....:|         .||:...:.|:..                   :|.:::..::.:|:
  Fly   929 SEDDEATANRFDVDLMMTPGSRANGTARTAHNRLIVPMLPPAPAGLSQQQLKRRHIVAAIVHSEN 993

  Fly   438 NYLDVLTALKTKFMGPLER----HLNQDELRLIFPRIRELVDIHTKFLDKLRESLTP-NAKVKMA 497
            :|:..|..|...:..|||.    .||..::..:|..:.:::..|..|...|.|.:.. :...|:.
  Fly   994 SYVATLQRLVNDYKKPLEECSPPVLNPVKIATLFHCLPDILHSHKLFRISLAECVRNWDRDEKIG 1058

  Fly   498 QVFLD-FREPFL--IYGEFCSLLLGAIDY----------LADVCKKNQIIDQLVQKCERDYNVGK 549
            ..|:. |.:|.|  ||..|.:....|::.          |||..|..||...           .:
  Fly  1059 DCFVSAFGKPQLLEIYSGFINNFSAAMELAKMEEKRKSALADFFKVKQISAH-----------DR 1112

  Fly   550 LQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVII 614
            |....::..|:||..::.|.|..|:|.|...|.|..||:.|...:..:::.:||.||:::.   .
  Fly  1113 LSFFGLMVKPVQRFPQFILFLQDLLKYTPQGHHDRMSLQLALSQLELLAELLNESKREAEQ---Y 1174

  Fly   615 QKVKDSICDIHLLQNGNGSDLLQYG----------RLLL--DGELHIKAHED---QKTKLRYAFV 664
            |..|:.:..|....|.....|....          |.||  |...|::.::.   .|.|.|...:
  Fly  1175 QAFKEMLGHISGTFNARSLSLSSVSVSDSAGGHRPRYLLREDNVTHMEFNQAGFIVKCKQRRLLL 1239

  Fly   665 F-DKIL---IMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGR 708
            . ||::   :..|..|......:.|::....:.|..:..:.:..|:.|
  Fly  1240 LNDKVICVSVAPKQSHDFGATEKLTFKWMFPVNDVEIVDNSTSATLSR 1287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vav	NP_001097030.1	CH	20..132	CDD:278723
		RhoGEF	428..603	CDD:279015	43/192 (22%)
		PH_Vav	624..753	CDD:269930	19/104 (18%)
		PH	641..749	CDD:278594	15/77 (19%)
		C1_1	761..804	CDD:278556
		SH2_Vav_family	824..934	CDD:198193
		SH3	940..993	CDD:302595
CG43658	NP_001259643.1	RhoGEF	984..1153	CDD:279015	42/179 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910