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Protein Alignment Vav and Prex1

DIOPT Version :9

Sequence 1:	NP_001097030.1	Gene:	Vav / 32920	FlyBaseID:	FBgn0040068	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	NP_808450.2	Gene:	Prex1 / 277360	MGIID:	3040696	Length:	1650	Species:	Mus musculus

Alignment Length:	633	Identity:	153/633 - (24%)
Similarity:	234/633 - (36%)	Gaps:	187/633 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   406 CALHRTSRSQTASSTSFEQRDYVIRELIDTESNYLDVLTALKTKFM--------GPLERHLNQDE 462
            ||..|.|..|      ...|..|:.|::.||.:|:..|..|::.|:        ..:|:.|.::.
Mouse    32 CAAARDSERQ------LRLRLCVLNEILGTERDYVGTLRFLQSAFLQRIRQNVADSVEKGLTEEN 90

  Fly   463 LRLIFPRIRELVDIHTKFLDKLRESL--TPNAKVKMAQVFLDFREPFLIYGEFCSLLLGAIDYLA 525
            ::::|..|.:::::|..||..|...|  .|.::.::..|||.|::.|.:|.|:||....|:..|.
Mouse    91 VKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLV 155

  Fly   526 DVCKKNQIIDQLVQKCERDYNVGKLQLRDI-----LSVPMQRILKYHLLLDKLVKETSPLHDDYR 585
            :: .|...:...:..|   ..:|..:..||     |..|:|||.||.|||.:|.|.|...|.|:.
Mouse   156 EL-NKVPAVRAFLLSC---MLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHT 216

  Fly   586 SLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQY-GRLLLDGE-LH 648
            :::.|.:||..|...|||.||..:.|..:::::..|      :...||:|... ..|||.|. |.
Mouse   217 AVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHI------EGWEGSNLTDICTELLLQGNLLK 275

  Fly   649 IKAHEDQKTKLRYAFVFDKILIMVKALHIKTGDMQ------------YTYRDSHN---------- 691
            |.|...|:   |..|:||.:|:..|.....||..:            |.:|...|
Mouse   276 ISAGNIQE---RAFFLFDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVE 337

  Fly   692 --LADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTA----FTLYLKSEHERDKWRKAL---TEA 747
              .|||     ||.         .|.:....|...||    |....|:..|:.||..||   .|.
Mouse   338 DGTADY-----HSN---------GYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDALIREREQ 388

  Fly   748 MESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGR--IHQGYRCKVCQISVHKGCISSTGRCK 810
            .|||:      ...:.:.|...|.          ||.  .|.....||..|...:..:|:..:|
Mouse   389 RESLK------LGMERDAYVMIAE----------KGEKLYHMMMSKKVNLIKDRRRKLSTVPKC- 436

  Fly   811 QNPVSVPPPVCDRQLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVRPQGPSTAHETMYALSLKT 875
                                |.||   |..|..||...|.                       ||
Mouse   437 --------------------FLGN---EFVAWLLEIGEIS-----------------------KT 455

  Fly   876 DDNVIKHMKINQENSGDSMLYCLSSRRHFKTIVELVSYYERNDLGENFA----------GLN--- 927
            ::.|    .:.|....:.:::.:|.:..||.  |.|.|..|.|.|...|          |:.
Mouse   456 EEGV----NLGQALLENGIIHHVSDKHQFKN--EQVMYRFRYDDGTYKARSELEDIMSKGVRLYC 514

  Fly   928 --QSLQWP-----------YKEVI-ATALYDYEPKAGSNQLQLRTDCQ 961
              .||..|           ||.|: .:.|.|:        |..:.|||
Mouse   515 RLHSLYAPVIKDRDYHLKTYKSVVPGSKLVDW--------LLAQGDCQ 554

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.