| Sequence 1: | NP_001097030.1 | Gene: | Vav / 32920 | FlyBaseID: | FBgn0040068 | Length: | 1001 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_064317.2 | Gene: | Ptpn4 / 19258 | MGIID: | 1099792 | Length: | 926 | Species: | Mus musculus |
| Alignment Length: | 634 | Identity: | 109/634 - (17%) |
|---|---|---|---|
| Similarity: | 205/634 - (32%) | Gaps: | 196/634 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 329 RLQRAAAAVYNYRSSMASTEHEYAYIYSEDDEKVYEDLCYVTFQAKAKPEVTTDNIACNGTGYDH 393
Fly 394 T------NTKEE-EVYQDLCALHRTSRSQTASSTSFEQRDYVIRELIDTESN---YLDVLTALKT 448
Fly 449 KFMGPLERHLNQDELRLIFPRIRELVDIHTKFL----DKLRESLTPNAKVKMAQVFLDFREPFLI 509
Fly 510 YGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKL---QLRDILSVPMQRILKYHLLLD 571
Fly 572 KLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLL 636
Fly 637 QYGRLLLDGELHIKAHEDQKTKLRYAFVFDKILIMV-KALHIKTGDMQYTYRDSHNLADYRVEQS 700
Fly 701 HSRRTIGRDTRFKYQLLLARKSGKTA--FTL----------------YLKSEHERDK-------- 739
Fly 740 --------W----RKAL------TEAMESLEPPGCQSTDHKMEIYTFDA----PTTCRHCSKFLK 782
Fly 783 GRIHQGYRCKVCQISVHKGCIS--STGRCKQNPVSV-------------PPPVCDRQLSEFNW-- 830
Fly 831 -FAGNMDRETAAHRLENRRIGTYLLRVRPQGPSTAHETMYALSLKTDDN 878 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Vav | NP_001097030.1 | CH | 20..132 | CDD:278723 | |
| RhoGEF | 428..603 | CDD:279015 | 34/184 (18%) | ||
| PH_Vav | 624..753 | CDD:269930 | 29/173 (17%) | ||
| PH | 641..749 | CDD:278594 | 24/152 (16%) | ||
| C1_1 | 761..804 | CDD:278556 | 7/46 (15%) | ||
| SH2_Vav_family | 824..934 | CDD:198193 | 11/58 (19%) | ||
| SH3 | 940..993 | CDD:302595 | |||
| Ptpn4 | NP_064317.2 | B41 | 30..222 | CDD:214604 | 47/246 (19%) |
| FERM_N | 33..97 | CDD:286467 | 13/73 (18%) | ||
| FERM_M | 115..222 | CDD:278785 | 28/135 (21%) | ||
| FERM_C_PTPN4_PTPN3_like | 216..310 | CDD:270010 | 18/105 (17%) | ||
| FA | 325..365 | CDD:285894 | 6/39 (15%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 379..412 | 8/34 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 429..474 | 6/44 (14%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 492..511 | 3/19 (16%) | |||
| PDZ_signaling | 515..602 | CDD:238492 | 3/11 (27%) | ||
| PTPc | 657..910 | CDD:214550 | |||
| PTPc | 682..909 | CDD:238006 | |||
| Substrate binding. /evidence=ECO:0000250 | 852..858 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||