| Sequence 1: | NP_001097030.1 | Gene: | Vav / 32920 | FlyBaseID: | FBgn0040068 | Length: | 1001 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001336023.1 | Gene: | ECT2 / 1894 | HGNCID: | 3155 | Length: | 958 | Species: | Homo sapiens |
| Alignment Length: | 615 | Identity: | 135/615 - (21%) |
|---|---|---|---|
| Similarity: | 231/615 - (37%) | Gaps: | 153/615 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 371 FQAKAKPEVTTDNIACNGTGYDHTNTKEEEV-YQDL---CALHRTSRSQTASSTSFEQRDYVIRE 431
Fly 432 LIDTESNYLDVLTALKTKFMGPLERH-------LNQDELRLIFPRIRELVDIHTKFLDKLRESLT 489
Fly 490 PN--AKVKMAQVFLDFRE-------PFLIYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDY 545
Fly 546 --------------NVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMID 596
Fly 597 VSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLD--GELHIKAHEDQKTKL 659
Fly 660 RYAFVFDKILIMVKALHIKTGDMQYTYRDSHNLAD--------YRVEQSHSRRTIG-RDTRFKYQ 715
Fly 716 --LLLARKSGKTAFTL----YLKSEHERDKWRKALTEAMESLEPPGCQSTDHKM---------EI 765
Fly 766 YTFDAPTTCRHCSKFLKGRIHQGYRC----KVCQISVHKGCISSTGRCK-QNPVSVPPPVCDRQL 825
Fly 826 SEFNWFAGNMDRETAAHRLENRRIGTYLLRVRPQGPSTAHETMYALSLKTDDNVI---KHMKINQ 887
Fly 888 ENS--GDSMLYCLSSRRH------FKTIVE 909 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Vav | NP_001097030.1 | CH | 20..132 | CDD:278723 | |
| RhoGEF | 428..603 | CDD:279015 | 56/204 (27%) | ||
| PH_Vav | 624..753 | CDD:269930 | 26/145 (18%) | ||
| PH | 641..749 | CDD:278594 | 22/124 (18%) | ||
| C1_1 | 761..804 | CDD:278556 | 8/55 (15%) | ||
| SH2_Vav_family | 824..934 | CDD:198193 | 18/97 (19%) | ||
| SH3 | 940..993 | CDD:302595 | |||
| ECT2 | NP_001336023.1 | PTCB-BRCT | 179..242 | CDD:315420 | |
| BRCT | 266..341 | CDD:306918 | |||
| Nuclear localization signal | 378..382 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 388..449 | 13/53 (25%) | |||
| Nuclear localization signal | 401..405 | 0/3 (0%) | |||
| RhoGEF | 456..640 | CDD:214619 | 56/204 (27%) | ||
| PH_Ect2 | 631..804 | CDD:269936 | 35/186 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 857..884 | 7/63 (11%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||