DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vav and cpn-2

DIOPT Version :9

Sequence 1:	NP_001097030.1	Gene:	Vav / 32920	FlyBaseID:	FBgn0040068	Length:	1001	Species:	Drosophila melanogaster
Sequence 2:	NP_493713.2	Gene:	cpn-2 / 173424	WormBaseID:	WBGene00000778	Length:	203	Species:	Caenorhabditis elegans

Alignment Length:	106	Identity:	36/106 - (33%)
Similarity:	54/106 - (50%)	Gaps:	7/106 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LRDGVLLCNLVIHLDPSSLDPREFNRKPQMAQFLCSKNIKLFLDVCHNNFGIRDADLFEPTMLYD 118
            |:|||:||.|:..||||.  ...:|:||:|| |...:||..|| .....||:.:...|:...||:
Worm    59 LKDGVMLCKLIEKLDPSC--RVVYNKKPKMA-FPMMENISNFL-AAAKQFGVMEISCFQTVDLYE 119

  Fly   119 LTNFHRV---LITLSKLSQCRKVQQLHPDLIGFNLQLSPTE 156
            ....::|   |..|:.::|.|.....||..:....|.||.:
Worm   120 NKQCYKVIECLRLLAAVAQSRSSHLEHPAWVVKLAQSSPRQ 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vav	NP_001097030.1	CH	20..132	CDD:278723	29/80 (36%)
		RhoGEF	428..603	CDD:279015
		PH_Vav	624..753	CDD:269930
		PH	641..749	CDD:278594
		C1_1	761..804	CDD:278556
		SH2_Vav_family	824..934	CDD:198193
		SH3	940..993	CDD:302595
cpn-2	NP_493713.2	SCP1	14..187	CDD:227526	36/106 (34%)
		CH	25..133	CDD:278723	28/77 (36%)
		Calponin	173..196	CDD:278814
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910