Protein Alignment Hs3st-B and HS3ST3A1

DIOPT Version :10

• Sequence 1: NP_573370.1
• Gene: Hs3st-B / 32918
• FlyBaseID: FBgn0031005
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_006033.1
• Gene: HS3ST3A1 / 9955
• HGNCID: 5196
• Length: 406
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 204/421 - (48%)
• Similarity: 256/421 - (60%)
• Gaps: 70/421 - (16%)

  Fly     6 ATSAQPAMIVMSIWCSSLSLSSRSL--AIALVIC--VTLVYFSYSFNACL--------------- 51
            :|||:|.              |||:  ...|::|  :|.:|..|    ||
Human    11 STSAEPL--------------SRSIFRKFLLMLCSLLTSLYVFY----CLAERCQTLSGPVVGLS 57

  Fly    52 -------------LASISRSL----QQSNLRNLLALTS-------SPRNETNNAANSSSSNSSSS 92
                         ||...|.|    ..:..:.||.|..       :||::...||....|...|.
Human    58 GGGEEAGAPGGGVLAGGPRELAVWPAAAQRKRLLQLPQWRRRRPPAPRDDGEEAAWEEESPGLSG 122

  Fly    93 RNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLRPSRHLPDTLIIGVKKSGTRALLEFIRLHPDV 157
            ....|..|:..|:....:|      .||..:|   |:.||..:||||||.||||||||:|:||||
Human   123 GPGGSGAGSTVAEAPPGTL------ALLLDEG---SKQLPQAIIIGVKKGGTRALLEFLRVHPDV 178

  Fly   158 RAAGSEVHFFDRHYQRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVR 222
            ||.|:|.|||||.|.:||.|||..||.|::||||||||||||||:|.|.|:..|:..|||::|||
Human   179 RAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVR 243

  Fly   223 DPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGPVKIGVYARYLERWLLYFPLSQLL 287
            ||||||||||||..||:.|:..||.|.|.|.:..::||:|..::||:||::||.||.:||:.|:|
Human   244 DPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQML 308

  Fly   288 FISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCLFKSEARSTPHCLGKTKGRNHP 352
            |:||||||.|||.|:|||||||||||::|:||||||.|||||||.|:|..|.||||||||||.||
Human   309 FVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHP 373

  Fly   353 HIDPGAIERLREFYRPFNNKFYQLTGINFAW 383
            .||...:.||||||||||.||||:||.:|.|
Human   374 EIDREVVRRLREFYRPFNLKFYQMTGHDFGW 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_573370.1	Sulfotransfer_1	131..368	CDD:425820	157/236 (67%)
HS3ST3A1	NP_006033.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	92..134		9/41 (22%)
		Sulfotransfer_1	152..389	CDD:425820	157/236 (67%)