DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs3st-B and SULT2B1

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_814444.1	Gene:	SULT2B1 / 6820	HGNCID:	11459	Length:	365	Species:	Homo sapiens

Alignment Length:	208	Identity:	50/208 - (24%)
Similarity:	86/208 - (41%)	Gaps:	33/208 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 DTLIIGVKKSGTRALLEFIRLHPDVRAAGSEVHFFDRHYQRGLR-WYRHHMPYTIEGQITM-EKT 195
            |..||...||||..::|.|.|   :...|      |..:.|.:. |.|.....||.|..:: ::.
Human    62 DIFIITYPKSGTTWMIEIICL---ILKEG------DPSWIRSVPIWERAPWCETIVGAFSLPDQY 117

  Fly   196 PSYFVTKEVPQRVY---HMNPATKLLIVVRDP--VTRAISDYTQAASKKADMKLFEQLAFVNGSY 255
            ....::..:|.:::   ..:...|::.:.|:|  |..::..|::.|.:..|....:|.
Human   118 SPRLMSSHLPIQIFTKAFFSSKAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQF------- 175

  Fly   256 SVVDTNWGPVKIGVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLG-------LKR 313
             :.|...|.|:.|.:..:::.||........|||:.|.|..|....:.|:..|||       |..
Human   176 -LRDFLKGEVQFGSWFDHIKGWLRMKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGS 239

  Fly   314 VVTEKHFYFNATK 326
            ||.  |..|:|.|
Human   240 VVA--HSTFSAMK 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_001259702.1	Sulfotransfer_1	131..368	CDD:279075	50/208 (24%)
SULT2B1	NP_814444.1	Sulfotransfer_1	60..305	CDD:366246	50/208 (24%)
SULT2B1	NP_814444.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..365
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910